Myocardial perfusion imaging for predicting cardiac events in Japanese patients with advanced chronic kidney disease: 1-year interim report of the J-ACCESS 3 investigation

Abstract

MPI would be useful to stratify patients with advanced conservative CKD who are at high risk of cardiac events without adversely affecting damaged kidneys.

Prognostic study of cardiac events in Japanese patients with chronic kidney disease using ECG-gated myocardial Perfusion imaging: Final 3-year report of the J-ACCESS 3 study

“…Higher CRP levels were associated with cardiac events at 3 years of follow-up, but not after 1 year. 15 These findings suggest that higher CRP levels are linked to plaque formation or plaque rupture. Hase et al also significantly associated elevated CRP levels at the end of the predialysis phase among patients who had CKD but no CAD symptoms, with the occurrence of an initial cardiac event.…”

“…14,15 A total of 549 patients who registered at 62 institutions between April 2009 and September 2010 were assessed by stress-rest MPI within 2 months of registration and information about them including background, treatment, and clinical and imaging findings was collected.…”

Graphene Oxide/Ag Nanoparticles Cooperated with Simvastatin as a High Sensitive X‐Ray Computed Tomography Imaging Agent for Diagnosis of Renal Dysfunctions

“…[46,47] So the rapid diagnosis of kidney disease is conducive to avoid the emergence of renal failure and complications. [48] The diagnosis methods of kidney www.advancedsciencenews.com www.advhealthmat.de disease include biopsy of IgAN, determination of CysC and BUN in serum, ultrasonography, intravenous pyelography, and CT imaging and so on. [49,50] Compared with biopsy and blood test, renal imaging investigations demonstrating a decrease in length of both kidneys combined with either bumpy contours or signs of renal papillary necrosis showed a high sensitivity and specificity for diagnosing the disease.…”

Prognostic Value of Major Cardiac Event Risk Score Estimated With Gated Myocardial Perfusion Imaging in Japanese Patients With Coronary Artery Disease

“…2) Myocardial perfusion single photon emission computed tomography (SPECT) is widely recognized as a useful imaging methodology for the prediction of future cardiac events in patients with known or suspected CAD since the reports of Hachamovitch, et al 3,4) Also, in Japan, myocardial perfusion SPECT has commonly been used to predict cardiac events in patients with CAD. Risk stratification of cardiac events by nuclear cardiology has been demonstrated in some large-scale prognostic studies including the multicenter prospective Japanese Assessment of Cardiac Events and Survival Study in patients with ischemic heart disease (J-ACCESS), 5) in asymptomatic patients with type 2 diabetes (J-ACCESS 2), 6) in patients with chronic kidney disease (J-ACCESS 3), 7) and in another single-center large-scale prospective study. 8) Nakajima, et al 9) published a Heart Risk Table, which is the first cardiac event risk score predicting the risk of major cardiac events (MCEs) in Japanese patients with CAD within 3 years, prepared on the basis of predictors obtained from the J-ACCESS database (n = 2,395).…”