2024
DOI: 10.1002/jcp.31199
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Myocardial proteome changes in aortic stenosis rats subjected to long‐term aerobic exercise

Gustavo Augusto Ferreira Mota,
Sérgio Luiz Borges de Souza,
Danielle Fernandes Vileigas
et al.

Abstract: The effects of exercise training (ET) on the heart of aortic stenosis (AS) rats are controversial and the mechanisms involved in alterations induced by ET have been poorly clarified. In this study, we analyzed the myocardial proteome to identify proteins modulated by moderate‐intensity aerobic ET in rats with chronic supravalvular AS. Wistar rats were divided into four groups: sedentary control (C‐Sed), exercised control (C‐Ex), sedentary aortic stenosis (AS‐Sed), and exercised AS (AS‐Ex). ET consisted of five… Show more

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