1999
DOI: 10.1016/s0344-0338(99)80044-2
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Myofibroblastoma of the Breast with Hemangiopericytoma-like Pattern and Pleomorphic Lipoma-like areas

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Cited by 36 publications
(32 citation statements)
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“…For example, myofibroblastomas with leiomyomatous differentiation and pleomorphic lipoma-like areas have been reported. 7,8 The cytologic differential diagnosis of BM on FNAC has been extensively described in other reports and is not repeated here. [1][2][3][4][5] However, we would like to comment on a cytologic feature that has been underrecognized.…”
Section: Discussionmentioning
confidence: 99%
“…For example, myofibroblastomas with leiomyomatous differentiation and pleomorphic lipoma-like areas have been reported. 7,8 The cytologic differential diagnosis of BM on FNAC has been extensively described in other reports and is not repeated here. [1][2][3][4][5] However, we would like to comment on a cytologic feature that has been underrecognized.…”
Section: Discussionmentioning
confidence: 99%
“…Some of these cases had been previously reported in literature as small series or single case reports [39,40,41,42,43]. The clinical data were obtained from the medical records of patients or contributing pathologists.…”
Section: Methodsmentioning
confidence: 99%
“…Occasionally multi-nucleated giant cells closely reminiscent of floret-like cells of pleomorphic lipoma of soft tissues were observed (cases no. 3 and no.10) [40].…”
Section: Cytological Atypiamentioning
confidence: 97%
“…Although the presence of myxoid areas or atypical cells has been documented in some breast myofibroblastomas [1,3,5,6], their association in the same tumour could pose diagnostic problems with some malignant myxoid neoplasms. However, the absence of infiltrative margins, high mitotic activity, atypical mitoses, and necrosis argues against malignancy.…”
mentioning
confidence: 99%
“…Discrimination between myofibroblastoma and spindle cell lipoma/ solitary fibrous tumour may be difficult, as they are closely related neoplasms, likely arising from a common mammary stromal stem cell capable to differentiate along several [4][5][6]. This hypothesis is supported by the fact that all these tumours share some morphological and immunohistochemical features and by the recognition of hybrid tumours that simultaneously exhibit features of MFB and solitary fibrous tumour or MFB and spindle cell/pleomorphic lipoma [3,5,6]. Cytogenetic analyses, revealing that spindle cell lipoma and myofibroblastoma have similar chromosome 13 rearrangements associated with the loss of the 13q14 chromosomal region [2,7], seem to confirm what we have previously postulated.…”
mentioning
confidence: 99%