Myositis Ossificans as a Complication of Tetanus

Pitts, Neal C.

doi:10.1001/jama.1964.03070030059022

Cited by 11 publications

(3 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Interestingly, all the previous reports of myositis ossificans in association with tetanus tell a nearly identical story of ARDS-induced respiratory failure, at least 3-4 weeks of ventilator dependence, and muscle paralytic/relaxant therapy with subsequent development of myositis ossificans [4][5][6][7]. The common denominator is prolonged immobility reinforced by muscle paralytic/relaxant therapy and covert trauma secondary to constant passive pressure on immobilized joints.…”

Section: Discussionmentioning

confidence: 98%

Generalized periarticular myositis ossificans as a complication of pharmacologically induced paralysis

Ackman

Rosenthal

1995

Skeletal Radiol.

View full text Add to dashboard Cite

To our knowledge, no previous direct associations have been made between generalized myositis ossificans and pharmacological therapy. We report a case of generalized periarticular myositis ossificans associated with the use of curare and diazepam. The previously reported associations of myositis ossificans with tetanus and burns may be misleading. It is possible that it is not the disease process itself (e.g., tetanus, severe burn) that precipitates heterotopic ossification, but the treatment of these ailments. These observations suggest the importance of early mobilization and restrained use of immobilizing drugs. Further investigation is warranted with regard to the predisposing factors of generalized myositis ossificans and to its prevention.

show abstract

Section: Discussionmentioning

confidence: 98%

Generalized periarticular myositis ossificans as a complication of pharmacologically induced paralysis

Ackman

Rosenthal

1995

Skeletal Radiol.

View full text Add to dashboard Cite

show abstract

“…Previous reports have included cases of tetanus and odontogenic infection (12, 13). In a report of MO associated with pyogenic arthritis in pediatric patients, there were cases of post-pyogenic arthritis of the hip (14).…”

Section: Discussionmentioning

confidence: 99%

Myositis Ossificans of the Hip Due to Pyogenic Arthritis Caused by <i>Campylobacter fetus</i> Subspecies <i>fetus</i>

et al. 2017

View full text Add to dashboard Cite

A 61-year-old woman was admitted with severe hip pain causing immobility and high serum levels of inflammatory markers. The patient had a medical history of diabetes. She had been scheduled to undergo right hip replacement surgery for the treatment of osteoarthritis associated with gradually progressive pain. On admission, an enhanced abdominal computed tomography scan showed an abnormal increase in synovial fluid surrounding the right ilium, with piriformis muscle calcification. Subsequent blood and specimen cultures identified Campylobacter fetus subspecies fetus. This is a rare report of a case of myositis ossificans followed by C. fetus pyogenic arthritis of the hip.

show abstract

“…Only 13 such cases associated with tetanus have been reported in the literature [2,4,6,14,16,18,20]. In most cases, heterotopic bone formation gives rise to definite clinical symptoms such as a local mass causing pain and limitation of joint movement, often accompanied by fever.…”

Section: Discussionmentioning

confidence: 99%

Hyperostosis and osteoarthritis in patients surviving after tetanus

1994

View full text Add to dashboard Cite

Twenty patients (12 men and 8 women) who had survived tetanus were examined for bone and joint abnormalities, 1-9 years after the disease. The radiographic findings in the elbows were abnormal in 13 out of 20 patients, as were the shoulders of all 3 patients examined. Insertion hyperostoses were found at the elbow and/or in the shoulder region in 5 (25%) of the patients. The hyperostoses were bilateral in 3 patients. One of the patients with hyperostoses also had calcifications in the soft tissue of the elbow. The abnormalities were associated with mild clinical symptoms. Trauma to the periosteum caused by repeated traction of muscular contractions is possibly the causative mechanism. Twelve patients (60%) had osteoarthritis of the elbow joint presumably secondary to the violent stress to the joint.

show abstract

Myositis Ossificans as a Complication of Tetanus

Cited by 11 publications

References 2 publications

Generalized periarticular myositis ossificans as a complication of pharmacologically induced paralysis

Generalized periarticular myositis ossificans as a complication of pharmacologically induced paralysis

Myositis Ossificans of the Hip Due to Pyogenic Arthritis Caused by <i>Campylobacter fetus</i> Subspecies <i>fetus</i>

Hyperostosis and osteoarthritis in patients surviving after tetanus

Contact Info

Product

Resources

About