Mytilidae as model organisms in the marine ecotoxicology of pharmaceuticals - A review

Świacka, Klaudia; Maculewicz, Jakub; Smolarz, Katarzyna; Szaniawska, Anna; Caban, Magda

doi:10.1016/j.envpol.2019.113082

Cited by 48 publications

(19 citation statements)

References 169 publications

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“…Among them, the high filter-feeding capacity shown by M. galloprovincialis (about 50 mL of seawater per min (Famme et al, 1986)) makes this species an efficient accumulator of pollutants from the environment, leading to the opportunity to evaluate the concentration and bioavailability of toxic agents in situ. Moreover, M. galloprovincialis constitutes a source of food and habitat for many other marine species (Beyer et al, 2017;Świacka, et al, 2019), therefore contributing to trophic transfer of pollutants (Farrell and Nelson 2013;Larsen et al, 2016). Focusing on CeO 2 NPs, a previous study on M. galloprovincialis reported that most of the CeO 2 NPs filtered from the water column were ejected through pseudo-feces, but a non-negligible fraction could also bioaccumulate in tissues upon long-term exposure to CeO 2 NPs in the mg L -1 range (Conway et al, 2014).…”

Section: Effects Of Ceo 2 Nps and Hg 2+mentioning

confidence: 99%

Will temperature rise change the biochemical alterations induced in Mytilus galloprovincialis by cerium oxide nanoparticles and mercury?

Morosetti

Freitas

Pereira

et al. 2020

Environmental Research

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Section: Effects Of Ceo 2 Nps and Hg 2+mentioning

confidence: 99%

Will temperature rise change the biochemical alterations induced in Mytilus galloprovincialis by cerium oxide nanoparticles and mercury?

Morosetti

Freitas

Pereira

et al. 2020

Environmental Research

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“…No other effects on measured oxidative stress biomarkers, including GPx activity, were observed. Swiacka, Maculewicz, Smolarz, Szaniawska, and Caban (2019) reviewed the use of mussels in both lab and field pharmaceutical toxicology experiments. Studies with nonsteroidal anti-inflammatory drugs revealed effects on osmosis, energy balance, membrane stability, byssal thread strength and abundance, metabolism and general condition factors.…”

Section: Pharmaceuticalsmentioning

confidence: 99%

Effects of pollution on marine organisms

Mearns

Morrison

Arthur³

et al. 2020

Water Environment Research

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This review covers selected 2019 articles on the biological effects of pollutants, including human physical disturbances, on marine and estuarine plants, animals, ecosystems, and habitats. The review, based largely on journal articles, covers field, and laboratory measurement activities (bioaccumulation of contaminants, field assessment surveys, toxicity testing, and biomarkers) as well as pollution issues of current interest including endocrine disrupters, emerging contaminants, wastewater discharges, marine debris, dredging, and disposal. Special emphasis is placed on effects of oil spills and marine debris due largely to the 2010 Deepwater Horizon oil blowout in the Gulf of Mexico and proliferation of data on the assimilation and effects of marine debris microparticulates. Several topical areas reviewed in the past (e.g., mass mortalities ocean acidification) were dropped this year. The focus of this review is on effects, not on pollutant sources, chemistry, fate, or transport. There is considerable overlap across subject areas (e.g., some bioaccumulation data may be appeared in other topical categories such as effects of wastewater discharges, or biomarker studies appearing in oil toxicity literature). Therefore, we strongly urge readers to use keyword searching of the text and references to locate related but distributed information. Although nearly 400 papers are cited, these now represent a fraction of the literature on these subjects. Use this review mainly as a starting point. And please consult the original papers before citing them.

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“…This species is therefore often used as a sentinel organism for the monitoring of coastal water pollution (mussel watch programs) [ 25 ]. Additionally, Mytilus species have been extensively used as model organisms to study the effects of pollutants in laboratory studies [ 26 , 27 ].…”

Section: Introductionmentioning

confidence: 99%

Early Biological Modulations Resulting from 1-Week Venlafaxine Exposure of Marine Mussels Mytilus galloprovincialis Determined by a Metabolomic Approach

et al. 2022

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There is growing evidence of the presence of pharmaceuticals in natural waters and their accumulation in aquatic organisms. While their mode of action on non-target organisms is still not clearly understood, their effects warrant assessment. The present study assessed the metabolome of the Mediterranean mussel (Mytilus galloprovincialis) exposed to a 10 µg/L nominal concentration of the antidepressant venlafaxine (VLF) at 3 time-points (1, 3, and 7 days). Over the exposure period, we observed up- or down-modulations of 113 metabolites, belonging to several metabolisms, e.g., amino acids (phenylalanine, tyrosine, tryptophan, etc.), purine and pyrimidine metabolisms (adenosine, cyclic AMP, thymidine, etc.), and several other metabolites involved in diverse functions. Serotonin showed the same time-course modulation pattern in both male and female mussels, which was consistent with its mode of action in humans, i.e., after a slight decrease on the first day of exposure, its levels increased at day 7 in exposed mussels. We found that the modulation pattern of impacted metabolites was not constant over time and it was gender-specific, as male and female mussels responded differently to VLF exposure.

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Mytilidae as model organisms in the marine ecotoxicology of pharmaceuticals - A review

Cited by 48 publications

References 169 publications

Will temperature rise change the biochemical alterations induced in Mytilus galloprovincialis by cerium oxide nanoparticles and mercury?

Will temperature rise change the biochemical alterations induced in Mytilus galloprovincialis by cerium oxide nanoparticles and mercury?

Effects of pollution on marine organisms

Early Biological Modulations Resulting from 1-Week Venlafaxine Exposure of Marine Mussels Mytilus galloprovincialis Determined by a Metabolomic Approach

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