N-Heterosubstituted Amides

Microwave assisted N-chlorination of secondary amides

“…15,16 Many literature methods are reported for the synthesis of primary N-chloroamides. 17 Routes to synthesize secondary N-chloroamides include chlorination of secondary amides with NaCl in the presence of oxone, 18 t-butyl hypochlorite, 19-21 sodium hypochlorite, [22][23][24] and Nchlorosuccinimide. 25 These methods for the synthesis of secondary N-chloroamides have their own limitations.…”