“…The goal of this work is to evaluate the status quo, as evidenced by expert opinions in the field, to narrow the topic, and to isolate and underline the impact of these tools on the resulting architectures and following bio-related potential. Although our research spans diverse topics, from bioagents’ carriers, biosynthesis [ 9 , 10 , 11 ], genotypic mapping [ 12 , 13 , 14 , 15 , 16 ], and cell growth [ 17 , 18 ], to artificial water channels [ 19 , 20 , 21 , 22 ], and the exploration of investigative methods [ 23 , 24 ], the review considers the hot topics of drug and gene delivery, antioxidants development, and bioimaging. We addressed these topics by following five major themes: (i) temperature- and pH-responsive systems; (ii) glycodynameric frameworks; (iii) polymeric non-viral vectors; (iv) metallic nanoconjugates; and, (v) smart organic tools.…”