Naked-Eye and Near-Infrared Fluorescence Probe for Hydrazine and Its Applications in In Vitro and In Vivo Bioimaging

Zhang, Jianjian; Ning, Lulu; Liu, Ji-Ting; Wang, Jianxi; Yu, Biao; Liu, Xiaoyan; Yao, Xiaojun; Zhang, Ziping; Zhang, Haixia

doi:10.1021/acs.analchem.5b02527

Cited by 186 publications

(53 citation statements)

References 55 publications

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“…Chemosensor 131 (Figure 53) was sensitive to hydrazine (N 2 H 4 ). 177 The molecule contained an acetyl moiety as the sensing unit. Due to the blocked ICT process in the molecule, 131 exhibited no fluorescence, while hydrazine could remove the acetyl group and light up the fluorescence.…”

Section: Sensors Based On Modulating the Electron-donating Ability Ofmentioning

confidence: 99%

Recent Development of Chemosensors Based on Cyanine Platforms

et al. 2016

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The cyanine platforms including cyanine, hemicyanine, and squaraine are good candidates for developing chemosensors because of their excellent photophysical properties, outstanding biocompatibility, and low toxicity to living systems. A huge amount of research work involving chemosensors based on the cyanine platforms has emerged in recent years. This review focuses on the development from 2000 to 2015, in which cyanine, hemicyanine, and squaraine sensors will be separately summarized. In each section, a systematization according to the type of detection mechanism is established. The basic principles about the design of the chemosensors and their applications as bioimaging agents are clearly discussed. In addition, we emphasize the advances that have been made in improving the detection performance through incorporation of the chemosensors into nanoparticles.

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Section: Sensors Based On Modulating the Electron-donating Ability Ofmentioning

confidence: 99%

Recent Development of Chemosensors Based on Cyanine Platforms

et al. 2016

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“…Recently, Zhang et al . devised another NIR fluorescent probe 12 for selective and sensitive detection of hydrazine that operates based on deprotection of the acetyl group of probe 12 by reaction with hydrazine.…”

Section: Introductionmentioning

confidence: 99%

“…Images were taken after incubation for 0, 1, 5, 10, and 20 min, respectively. Reprinted with permission from Ref . Copyright (2015) American Chemical Society.…”

Section: Introductionmentioning

confidence: 99%

Recent Developments in Fluorometric and Colorimetric Chemodosimeters Targeted towards Hydrazine Sensing: Present Success and Future Possibilities

Manna¹,

Gangopadhyay

Maiti

et al. 2019

ChemistrySelect

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Recently, the design, synthesis and development of chemodosimeters for hydrazine with high selectivity and sensitivity has attracted tremendous attention due to its major contributions to human health and disease including applications in various platforms. In this review, we recapitulate different strategies for the design of reaction‐based colorimetric and fluorometric probes for the detection of hydrazine and their applications in hydrazine sensing in living systems. The sensing strategies for hydrazine have been divided into six categories: (a) cleavage of the acetoxy group; (b) the nucleophilic addition‐elimination on keto ester; (c) the nucleophilic substitution‐elimination to tandem cyclization on halo‐ester; (d) the nucleophilic addition reaction to phthalimide derivative to phthalhydrazide; (e) the chemical displacement of active methylene compound to hydrazone derivative and (f) Other different approaches. Additionally, a variety of techniques have been devised here for the detection of hydrazine over other comparable ions and neutral amines.

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“…Compound 6 was reported as a NIR and turn‐on fluorescent probe for hydrazine detection (Figure ) . Reaction of the probe with hydrazine removes the acetate moiety, producing the highly fluorescent NIR hemicyanine fluorophore.…”

Section: Probes Based On Acetyl Moietymentioning

confidence: 99%

Recent progress in the development of fluorescent probes for hydrazine

et al. 2018

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Hydrazine (N H ) is an important and commonly used chemical reagent for the preparation of textile dyes, pharmaceuticals, pesticides and so on. Despite its widespread industrial applications, hydrazine is highly toxic and exposure to this chemical can cause many symptoms and severe damage to the liver, kidneys, and central nervous system. As a consequence, many efforts have been devoted to the development of fluorescent probes for the selective sensing and/or imaging of N H . Although great efforts have been devoted in this area, the large number of important recent studies have not yet been systematically discussed in a review format so far. In this review, we have summarized the recently reported fluorescent N H probes, which are classified into several categories on the basis of the recognition moieties. Moreover, the sensing mechanism and probes designing strategy are also comprehensively discussed on aspects of the unique chemical characteristics of N H and the structures and spectral properties of fluorophores.

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Naked-Eye and Near-Infrared Fluorescence Probe for Hydrazine and Its Applications in In Vitro and In Vivo Bioimaging

Cited by 186 publications

References 55 publications

Recent Development of Chemosensors Based on Cyanine Platforms

Recent Development of Chemosensors Based on Cyanine Platforms

Recent Developments in Fluorometric and Colorimetric Chemodosimeters Targeted towards Hydrazine Sensing: Present Success and Future Possibilities

Recent progress in the development of fluorescent probes for hydrazine

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