Nano-ordered MCM-41-SO3H an efficient catalyst for the synthesis of N-substituted pyrroles in water

Abstract

Abstract. In this study, a mild and sustainable three-component passerini reaction in biodegradable deep eutectic solvent based choline chloride:urea (1:2) is described. The reaction proceeds at room temperature involving substituted benzaldehyde, benzoic acid, and cyclohexyl isocyanide with a short reaction time and good to excellent yields (65-90%) without tedious workup.