Nano polypyrrole-coated magnetic solid phase extraction followed by dispersive liquid phase microextraction for trace determination of megestrol acetate and levonorgestrel

Ebrahimpour, Behnam; Yamini, Yadollah; Seidi, Shahram; Tajik, Mohammad

doi:10.1016/j.aca.2015.05.025

Cited by 50 publications

(8 citation statements)

References 42 publications

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“…Since then, different miniaturised extraction methods have been released by research groups worldwide such as hollow‐fibre liquid‐phase microextraction (LPME) [12], dispersive liquid–liquid microextraction [13], electromembrane extraction [14], in‐tube solid‐phase microextraction [15], pipette‐tip SPE (PT‐SPE) [16], magnetic dispersive SPE (MDSPE) [17], and many other formats with innovative approaches. During the past decade, the exploitation of nanostructured materials in microextraction methods have facilitated these methods thanks to the ease of preparation, availability of required materials which are usually environmentally friendly, with high cleanup values and extraction efficiencies (EEs) [18]. Among different nanomaterials, Fe 3 O 4 nanoparticles (NPs) has been utilised as an excellent substrate which can be easily modified with different functional groups.…”

Section: Introductionmentioning

confidence: 99%

Trace analysis of Pb(II) in milk samples by Fe ₃ O ₄ @SiO ₂ @3‐chloropropyltriethoxysilane@o‐phenylendiamine nanoparticles as an unprecedented adsorbent for magnetic dispersive solid phase extraction

Ramezanpour

Raeisi

Shahidi

et al. 2020

Micro & Nano Letters

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In the present work, a magnetic dispersive solid-phase extraction method followed by flame atomic absorption spectrometry was used for extraction, preconcentration and determination of trace amounts of Pb(II) in milk samples. Fe 3 O 4 @SiO 2 @3chloropropyltriethoxysilane@o-phenylendiamine nanoparticles were synthesised and used as the adsorbent in the extraction procedure. The effective parameters of the extraction efficiency comprising pH of the sample solution, sorbent amount, extraction time, acidic concentration of the eluent and desorption time were optimised using a face-centred central composite design. Under the optimal conditions, the applied method offered suitable linearity in the range of 2.0-250 ng mL −1 , the limit of detection as low as 0.11 ng mL −1 , and high preconcentration factor of 66. The precision of the proposed method was evaluated by calculating the intra-day and inter-day relative standard deviation, which were <3.4 and 5.5%, respectively. The applicability of the method in real sample analysis was tested by analysing bovine milk samples. The relative recoveries in the range of 81.6-97.2% showed the suggested method is of appropriate accuracy in real sample analysis.

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Section: Introductionmentioning

confidence: 99%

Trace analysis of Pb(II) in milk samples by Fe ₃ O ₄ @SiO ₂ @3‐chloropropyltriethoxysilane@o‐phenylendiamine nanoparticles as an unprecedented adsorbent for magnetic dispersive solid phase extraction

Ramezanpour

Raeisi

Shahidi

et al. 2020

Micro & Nano Letters

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“…In this case, the solubility of the TAM in the aqueous phase decreased and extraction efficiency increased by extraction efficiency mass transfer to organic solvent. It is believed that addition of salt might change the physical properties of the Nernst diffusion film, reduce the diffusion rates of solutes from water to the adsorbent surface, and ultimately decrease the extraction efficiency . Based on these results, the 10% w/v of salt was selected as the optimum amount of NaCl concentration for the subsequent experiments.…”

Section: Resultsmentioning

confidence: 99%

Electrospun polyethylene terephthalate/graphene oxide nanofibrous membrane followed by HPLC for the separation and determination of tamoxifen in human blood plasma

Sereshti

Bakhtiari

Najarzadekan

et al. 2017

J of Separation Science

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An electrospun polyethylene terephthalate/graphene oxide nanofibrous mat was fabricated and used as an effective and novel membrane for the solid-phase extraction of tamoxifen in human blood plasma samples before detection by high-performance liquid chromatography. The membrane was characterized by some identification techniques, such as FTIR spectroscopy, X-ray diffraction, and scanning electron microscopy. The effective variables of the extraction procedure including desorption condition (type and volume of the eluent), adsorbent dose, pH of sample solution, salt concentration, and sample loading time were investigated and their optimum values were obtained using one factor at a time methodology. Under the optimized conditions, the results showed wide linear concentration range of 5-2000 ng/mL with a determination coefficient of 0.992. The limits of detection and limits of quantification were 1.3 and 5.0 ng/mL, respectively. The intra-day and inter-day precisions were 3.4 and 4.6%, respectively. The method was successfully applied to determination of tamoxifen in the blood plasma samples and satisfactory relative recoveries (92.6-98.3 %) were achieved.

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“…Levonorgestrel is extensively used as an active substance in certain contraceptive therapies and hormone replacement therapy. It is well known that steroid hormones are compounds that have repercussions on the endocrine gland, exerting influence on endocrine function even at extremely low concentrations [4].…”

Section: Introductionmentioning

confidence: 99%

Characterization and in vitro Evaluation of a New Levonorgestrel Silver Liposomes

Rădulescu¹,

Utescu²,

Borcan³

et al. 2020

Rev. Chim.

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Levonorgestrel is the most widely used synthetic hormone due in particular to strong progestin and anti-ovulatory effects, without estrogenic effects, being also used in hormone supportive therapy and found in preclinical studies for the prevention / occurrence of malignant processes. In order to be able to eliminate the adverse effects but to benefit at the same time from the beneficial biological effects, the posibility of obtaining effective and safe biocompatible formulations is studied. In the present research silver nanoparticles loaded with lenorgestrel were obtained and were subsequently included in a liposomal transporter system. Physico-chemical characterizations showed good stability of the liposomal systems obtained and dimensions compatible with the biological environment. In vitro data conducted on breast cells (MCF 10A and MCF7) revealed a dose-dependent influence in terms of cell viability with no significant changes at low concentration of samples (0.1 μM), while higher concentration was associated with a decrease of the viable breast adenocarcinoma cells especially in the case of silver nanoparticles.

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Nano polypyrrole-coated magnetic solid phase extraction followed by dispersive liquid phase microextraction for trace determination of megestrol acetate and levonorgestrel

Cited by 50 publications

References 42 publications

Trace analysis of Pb(II) in milk samples by Fe ₃ O ₄ @SiO ₂ @3‐chloropropyltriethoxysilane@o‐phenylendiamine nanoparticles as an unprecedented adsorbent for magnetic dispersive solid phase extraction

Trace analysis of Pb(II) in milk samples by Fe ₃ O ₄ @SiO ₂ @3‐chloropropyltriethoxysilane@o‐phenylendiamine nanoparticles as an unprecedented adsorbent for magnetic dispersive solid phase extraction

Electrospun polyethylene terephthalate/graphene oxide nanofibrous membrane followed by HPLC for the separation and determination of tamoxifen in human blood plasma

Characterization and in vitro Evaluation of a New Levonorgestrel Silver Liposomes

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Nano polypyrrole-coated magnetic solid phase extraction followed by dispersive liquid phase microextraction for trace determination of megestrol acetate and levonorgestrel

Cited by 50 publications

References 42 publications

Trace analysis of Pb(II) in milk samples by Fe 3 O 4 @SiO 2 @3‐chloropropyltriethoxysilane@o‐phenylendiamine nanoparticles as an unprecedented adsorbent for magnetic dispersive solid phase extraction

Trace analysis of Pb(II) in milk samples by Fe 3 O 4 @SiO 2 @3‐chloropropyltriethoxysilane@o‐phenylendiamine nanoparticles as an unprecedented adsorbent for magnetic dispersive solid phase extraction

Electrospun polyethylene terephthalate/graphene oxide nanofibrous membrane followed by HPLC for the separation and determination of tamoxifen in human blood plasma

Characterization and in vitro Evaluation of a New Levonorgestrel Silver Liposomes

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Trace analysis of Pb(II) in milk samples by Fe ₃ O ₄ @SiO ₂ @3‐chloropropyltriethoxysilane@o‐phenylendiamine nanoparticles as an unprecedented adsorbent for magnetic dispersive solid phase extraction

Trace analysis of Pb(II) in milk samples by Fe ₃ O ₄ @SiO ₂ @3‐chloropropyltriethoxysilane@o‐phenylendiamine nanoparticles as an unprecedented adsorbent for magnetic dispersive solid phase extraction