Nanomaterials based on phase change materials for antibacterial application

Xu, Wenjing; Xu, Linfeng; Jia, Weilu; Mao, Xinyu; Liu, Shiwei; Dong, Hui; Zhang, Haidong; Zhang, Yewei

doi:10.1039/d2bm01220k

Cited by 8 publications

(3 citation statements)

References 89 publications

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“…The different subgroups of PCMs have a wide range of physical, thermal and chemical properties, which can be used to design thermal energy storage systems. 151,[160][161][162][163] Solid-solid PCMs are made of polymer-based materials, such as polyurethanes and polyalcohols. Liquid-gas and gassolid PCMs are not commonly used because they require large volume and high-pressure systems.…”

Section: Pcm Composites For Controlled Heat Storagementioning

confidence: 99%

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Layered nanomaterials for renewable energy generation and storage

Nikitina,

Lavrentev,

Yurova

et al. 2024

Mater. Adv.

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Section: Pcm Composites For Controlled Heat Storagementioning

confidence: 99%

“…The different subgroups of PCMs have a wide range of physical, thermal and chemical properties, which can be used to design thermal energy storage systems. 151,160–163…”

Section: Application Of Phase Change Materials For Thermal Energy Sto...mentioning

confidence: 99%

Layered nanomaterials for renewable energy generation and storage

Nikitina,

Lavrentev,

Yurova

et al. 2024

Mater. Adv.

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“…Therefore, it is urgent to explore novel therapeutic modalities to tackle the problems of serious side effects and drug resistance of Sunitinib. Compared to traditional therapeutic methods of tumors, phototherapy, including photodynamic therapy (PDT) and photothermal therapy (PTT), has great potential applications in oncotherapy due to its high efficiency, low side effects, and no resistance [ 22 , 23 , 24 , 25 , 26 ]. PDT can transform oxygen into toxic reactive oxygen species (ROS), which have the capability to damage lipids, proteins, and DNA, and further kill cancer cells [ 27 , 28 , 29 ].…”

Section: Introductionmentioning

confidence: 99%

Multifunctional Nanoplatform Based on Sunitinib for Synergistic Phototherapy and Molecular Targeted Therapy of Hepatocellular Carcinoma

Yang

et al. 2023

Micromachines

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Hepatocellular carcinoma (HCC) is a tumor that poses a serious threat to human health, with an extremely low five-year survival rate due to its difficulty in early diagnosis and insensitivity to radiotherapy and chemotherapy. To improve the therapeutic efficiency of HCC, we developed a novel multifunctional nanoplatform (SCF NPs) with an amphiphilic polymer (Ce6-PEG2000-FA) and a multitarget tyrosine kinase inhibitor sunitinib. SCF NPs showed superior therapeutical efficiency for HCC due to the synergetic effect of molecular targeted therapy and phototherapy. The Ce6-PEG2000-FA not only serves as a nanocarrier with excellent biocompatibility but also can act as a therapeutic reagent for photothermal therapy (PTT) and photodynamic therapy (PDT). Furthermore, the folic acid group of Ce6-PEG2000-FA enhanced the active targeting performance of SCF NPs. As a multitargeted tyrosine kinase inhibitor, sunitinib in SCF NPs can play a role in molecular targeted therapies, including tumor growth inhibition and anti-angiogenesis. In vivo experiments, SCF NPs showed multimode imaging capabilities, which can be used for tumorous diagnosis and intraoperative navigation. Meanwhile, SCF NPs showed outstanding synergetic tumor inhibition ability. Tumors of SCF NPs group with laser radiation were eradicated without any recrudescence after 14 days of treatment. Such theranostic nanoparticles offer a novel therapeutic tactic for HCC.

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A Phase‐Change Mediated Intelligent Nanoplatform for Chemo/Photothermal/Photodynamic Therapy of Cancer

et al. 2022

Adv Healthcare Materials

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Up to now, chemotherapy is still the main strategy for cancer treatment. However, the emergence of chemo‐resistance and systemic side effects often seriously affects the treatment and prognosis. Herein, an intelligent nanoplatform based on dendritic mesoporous organosilica nanoparticles (DMON) is constructed. The encapsulated phase‐change material, 1‐tetradecanol (TD) can serve as a “doorkeeper” and enable the responsive release of drugs based on the temperature changes. Meanwhile, polyethylene glycol (PEG) is used to improve the dispersibility and biocompatibility. Cisplatin is chosen as the model of chemotherapy drug, which is co‐loaded with indocyanine green (ICG) in DMON to produce DMON‐PEG‐cisplatin/ICG‐TD (DPCIT). Exciting, the hyperthermia and reactive oxygen species induced by ICG under the NIR‐laser irradiation will initiate a phase transition of TD to release cisplatin, thus leading a combined therapy (chemo/photothermal/photodynamic therapy). The results indicated that under laser irradiation, DPCIT can kill cancer cells and inhibit tumor growth efficiently. In addition, the designed nanoplatform reveals minimal systemic toxicity in vivo, in contrast, the distinct liver damage can be observed by the direct treatment of cisplatin. Overall, this research may provide a general approach for the targeted delivery and controlled release of chemotherapy drugs to realize a cooperatively enhanced multimodal tumor therapy.

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Nanomaterials based on phase change materials for antibacterial application

Abstract: Bacterial infections seriously threaten human health. Although antibiotics can significantly treat infectious diseases, antibiotics abuse has brought a series of serious problems, such as multidrug-resistant bacteria, adverse effects, and so...

Cited by 8 publications

References 89 publications

Layered nanomaterials for renewable energy generation and storage

Layered nanomaterials for renewable energy generation and storage

Multifunctional Nanoplatform Based on Sunitinib for Synergistic Phototherapy and Molecular Targeted Therapy of Hepatocellular Carcinoma

A Phase‐Change Mediated Intelligent Nanoplatform for Chemo/Photothermal/Photodynamic Therapy of Cancer

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