“…Evidence from scientific studies demonstrates that ENMs and conventional materials have distinct psychochemical properties (size, shape, surface area, solubility, aggregates, agglomerates) (Marin-Bustamante et al, 2019;EFSA Scientific Committee, 2021;Tiwari et al, 2021;Bizymis & Tzia, 2022). The tiny particle has a greater surface area to volume ratio, which promotes greater reactivity and allows for novel applications that could be achieved using conventional-size materials (Thangadurai et al, 2020).…”