Nanosilver Application in Dental Cements

Abstract

Streptococcus mutans is the microorganism mostly responsible for initiation of tooth decay and also for the progression of an established lesion. Silver has been used for its antibacterial properties for many years, in different forms: ionised and elementary forms, as silver zeolites or as nanoparticles. The purpose of this study was to evaluate the antibacterial activity of three dental cements modified by nanosilver. Three cements were used: Sealapex, RelyX ARC, and Vitrebond. The cements were incorporated with 0.05 mL of silver nanoparticles solution. Control groups were prepared without silver. Six Petri plates with BHI were inoculated with S. mutans using sterile swabs. Three cavities were made in each agar plate (total = 18) and filled with the manipulated cements. They were incubated at 37• C for 48 h, and the inhibition halos were measured. The paired t-Test was used for statistical analysis (P < 0.05). No inhibition halos were obtained for Sealapex and Rely X, but Vitrebond showed bactericidal activity without silver and enhanced effect with silver incorporation.

Current Development of Silver Nanoparticle Preparation, Investigation, and Application in the Field of Medicine

“…A recent study by Chladek et al found that incorporating AgNPs into dental composites could reduce the microbial colonization of lining materials, enhancing the antifungal efficiency [111]. Similarly, AgNPs incorporated into endodontic fillings displayed an increased antibacterial effect against Streptococcus milleri, S. aureus, and E. faecalis [112].…”

Biomedical Uses of Silver Nanoparticles: From Roman Wine Cups to Biomedical Devices

“…(i) Dental Material (Class I) Studies have shown that AgNP infused dental filling cements have remarkable bactericidal effects [81]. Adding AgNP to orthodontic adhesives has also demonstrated notable antimicrobial properties, which in turn prevents enamel demineralization without jeopardizing the physical attributes of the adhesive in the process [82].…”

Evaluation of Antifungal Effect of Silver Nanoparticles Against Microsporum canis, Trichophyton mentagrophytes and Microsporum gypseum

“…Azimi et al (35) demonstrated that the greater antifungal effect of AgNPs on S. mutans and S. sanguis than Nigella sativa oil. The inhibitory effects of AgNPs on the growth of Gramnegative bacteria E. coli and Gram-positive bacteria S. aureus and S. mutans were confirmed (36,31). All of which appeared to be in agreement with our findings and other results reported about the antimicrobial activity of AgNPs.…”