Nanosilver as a new generation of nanoproduct in biomedical applications

Chaloupka, Karla; Malam, Yogeshkumar; Seifalian, Alexander M.

doi:10.1016/j.tibtech.2010.07.006

Cited by 1,307 publications

(866 citation statements)

References 78 publications

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“…Several authors have reported that silver has a direct or indirect effect on microbial cells [12][13][14][15] . The antimicrobial activity exhibited by silver has resulted in the widespread use of silver particles in bedding, water purification, toothpastes, shampoos, fabrics, deodorants, filters, kitchen utensils and toys.…”

Section: Discussionmentioning

confidence: 99%

“…The antimicrobial activity exhibited by silver has resulted in the widespread use of silver particles in bedding, water purification, toothpastes, shampoos, fabrics, deodorants, filters, kitchen utensils and toys. Using silver in the form of small-sized particles shows efficient antimicrobial properties due to their extremely large surface area, producing an effective contact with microorganisms [15] .…”

Section: Discussionmentioning

confidence: 99%

“…The morphology and crystal structure of the silver-based materials were characterized by scanning electron microscopy (SEM, 15 kV, S-2500 Hitachi, Japan) and X-ray diffraction (XRD) technique (30 kV, 30 mA, Cu Kα, λ=0.15418 nm, Bruker D8 with Ni Kβ filtered), respectively.…”

Section: Materials Characterizationmentioning

confidence: 99%

See 2 more Smart Citations

Antimicrobial effects of silver zeolite, silver zirconium phosphate silicate and silver zirconium phosphate against oral microorganisms

Saengmee-anupharb

Srikhirin

Thaweboon

et al. 2013

Asian Pacific Journal of Tropical Biomedicine

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Antimicrobial effects of silver zeolite, silver zirconium phosphate silicate and silver zirconium phosphate against oral microorganisms

Saengmee-anupharb

Srikhirin

Thaweboon

et al. 2013

Asian Pacific Journal of Tropical Biomedicine

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“…A further eight review articles in scientific journals followed in 2010 [11][12][13][14][15][16][17][18] , plus substantial reports commissioned by the Environmental Protection Agency (EPA) in the US (which ran to 221 pages) 19 and the Joint Research Centre (JRC) of the European Commission (426 pages) 20 . Two of the review articles in journals were also funded by the European Commission 14,16 .…”

mentioning

confidence: 99%

When enough is enough

Hansen

Baun

2012

Nature Nanotech

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“…15 Many researchers demonstrated effective use of AgNPs as treatment for burns, chronic ulcers, toxic epidermal necrolysis, and pemphigus. 16 Although AV gel and AgNPs are effective in the treatment of various types of ulcers, their efficiency in radiation combined oral ulceration has not yet been reported. Therefore, the aim of the current study was to evaluate the effects of topical application of these agents on oral ulcer healing in irradiated mice.…”

Section: Introductionmentioning

confidence: 99%

Therapeutic effect of Aloe vera and silver nanoparticles on acid-induced oral ulcer in gamma-irradiated mice

El-Batal

Ahmed

2018

Braz. oral res.

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Radiation combined injury, a life-threatening condition, has higher mortality than simple radiation injury. The aim of the present study was to analyze the efficiency of Aloe vera and silver nanoparticles in improving the healing of ulcerated oral mucosa after irradiation. Thirty male Albino mice were divided into five groups: control, radiation, Aloe vera (AV), silver nanoparticles (NS), and AV+NS. The mice were exposed to whole body 6Gy gamma-radiation. After one hour, 20% acetic acid was injected into the submucosal layer of the lower lip for ulcer induction. The animals received topical treatment with the assigned substances for 5 days. Lip specimens were subjected to hematoxylin and eosin and anti alpha-smooth muscle actin immunohistochemical staining. Results demonstrated occurance of ulcer three days post irradiation in all groups except in the AV+NS group where only epithelial detachment was developed. After seven days, data revealed persistent ulcer in radiation group, and almost normal epithelium in the AV+NS group. A significant reduction of epithelial thickness was detected in all groups at the third day as compared to control. At the seventh day, only the AV+NS group restored the epithelial thickness. Area percent of alpha-smooth muscle actin expression was significantly decreased in radiation group at the third day followed by significant increase at the seventh day. However, all treatment groups showed significant increase in alpha-smooth muscle actin at the third day, which decreased to normal level at the seventh day. Our study demonstrated the efficiency of Aloe vera and silver nanoparticles in enhancing ulcer healing after irradiation.

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Nanosilver as a new generation of nanoproduct in biomedical applications

Cited by 1,307 publications

References 78 publications

Antimicrobial effects of silver zeolite, silver zirconium phosphate silicate and silver zirconium phosphate against oral microorganisms

Antimicrobial effects of silver zeolite, silver zirconium phosphate silicate and silver zirconium phosphate against oral microorganisms

When enough is enough

Therapeutic effect of Aloe vera and silver nanoparticles on acid-induced oral ulcer in gamma-irradiated mice

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