Nanosilver fluoride as a caries arresting agent in children

Choubey, Shikha; Patil, Amol; Talekar, Abhinav L; Kalra, Dheeraj

doi:10.4103/jisppd.jisppd_224_22

Cited by 3 publications

(2 citation statements)

References 29 publications

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“…9. Another systematic review and meta-analysis in 2022 by Choubey Shikha et al found that NSF is an effective means for caries arrest in primary teeth (38).…”

Section: Evidence Based Studies On the Efficiency Of Nsfmentioning

confidence: 99%

Nano-silver Fluoride in Preventive Dentistry: A Literature Review

2024

IJFMR

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Dental caries is a problem that affects people's quality of life on a global scale, however secondary caries still accounts for the majority of reported failures. Based on its commercial and scientific potential, nanotechnology is recognized as an emergent 21st-century technology. It is expanding quickly and has numerous potential uses in dentistry. Newer silver compounds, such as Nano Silver Fluoride (NSF), have been discovered as a result of the demand for newer materials with an aesthetic focus and the establishment of a healthy balance between pathogenic and protective aspects. NSF is directly applied to the carious lesions to arrest and treat dental caries. It can be advantageous to treat dental caries in children since the management of dental caries with NSF is noninvasive and very comfortable to perform. This review offers an in-depth exploration of the progression, functioning, and practical implications of NSF in the prevention of dental caries.

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“…9. Another systematic review and meta-analysis in 2022 by Choubey Shikha et al found that NSF is an effective means for caries arrest in primary teeth (38).…”

Section: Evidence Based Studies On the Efficiency Of Nsfmentioning

confidence: 99%

Nano-silver Fluoride in Preventive Dentistry: A Literature Review

2024

IJFMR

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“…This damages the cell membrane and interferes with DNA replication leading to bacterial cell death [ 22 ]. Evidence showed the anti-caries property and better efficacy of NSF than the control in ECC arrest [ 19 , 23 , 24 ].…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of nanosilver fluoride and silver diamine fluoride in arresting early childhood caries: a randomized controlled clinical trial

Quritum,

Abdella,

Amer

et al. 2024

BMC Oral Health

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Background One of the most prevalent health problems affecting children worldwide is untreated caries in primary teeth. Agents to arrest caries are used to manage untreated decay in children in disadvantaged communities. Nano Silver Fluoride (NSF) overcomes the staining problems of Silver Diamine Fluoride (SDF). This study compared the clinical cariostatic effect of NSF to 38% SDF for arresting caries lesions. Methods The study included 360 children younger than 4 years, with at least one active lesion, ICDAS score ≥ 3, recruited from nurseries in a rural area in Alexandria, Egypt, in 2022. They were randomly assigned to receive a single application of NSF at baseline, or two applications of SDF at baseline and after 6 months. The arrest of active carious lesions was assessed after 6 and 12 months using ICDAS criteria, and parents’ satisfaction with child appearance was also assessed. Chi-Square test was used to compare the groups and multi-level multiple logistic regression was used to assess the effect of the intervention on caries arrest at lesion level and binary logistic regression was used to assess the effect at patient level. Results 1853 active lesions were included in children whose mean (SD) age was 42.3 (8.2) months. The arrest rate was significantly higher in the NSF than the SDF group at lesion level (78.4% and 65.0% at 6 months and 71.3% and 56.3% at 12 months, p < 0.001). In regression analysis, NSF had significantly higher odds of caries arrest than SDF at lesion level (at 6 months, AOR = 2.57, 95% CI: 1.55, 4.26 and at 12 month, AOR = 3.27, 95% CI: 1.89, 5.67). Parents of children receiving NSF had significantly greater satisfaction with their children’s dental appearance than those receiving SDF: (97.2% and 76.1%, respectively, p < 0.001). Conclusion NSF demonstrated greater effectiveness in arresting caries in preschool children without inducing black staining of teeth and with greater parental satisfaction than SDF. NSF can be an alternative to SDF in arresting caries especially in underprivileged communities. Trial registration The trial was registered in the clinicaltrials.gov registry (#NCT05255913)-16/02/2022.

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