2016
DOI: 10.2174/1567201813666160101120452
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Nanosuspension: Principles, Perspectives and Practices

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Cited by 31 publications
(19 citation statements)
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“…Therefore, to improve the thermodynamic stability, the nanoparticles showed a tendency to aggregate, resulting in a slight increase in the particle size. 49 The results reported earlier indicate that the optimized nanosuspension formulation was physically and chemically stable with a shelf life of at least 6 months, which might be due to the presence of BSA. Moreover, the Tween-80 used in the formulation adequately covers the surface of the particles, which could provide sufficient steric repulsion between particles.…”
Section: Stability Studiesmentioning
confidence: 83%
“…Therefore, to improve the thermodynamic stability, the nanoparticles showed a tendency to aggregate, resulting in a slight increase in the particle size. 49 The results reported earlier indicate that the optimized nanosuspension formulation was physically and chemically stable with a shelf life of at least 6 months, which might be due to the presence of BSA. Moreover, the Tween-80 used in the formulation adequately covers the surface of the particles, which could provide sufficient steric repulsion between particles.…”
Section: Stability Studiesmentioning
confidence: 83%
“…In this approach, submicron particles are formed which get stabilized by use of steric and electrostatic stabilizers [21]. Among nanotechnology approaches that are used for the formulation of lipophilic drugs, nanosuspension (NS) has been reported as one of the most promising techniques to improve the dissolution rate limited bioavailability of such drugs [22]. In general, bottom up and top down techniques are used to prepare NS [22,23].…”
Section: Introductionmentioning
confidence: 99%
“…Among nanotechnology approaches that are used for the formulation of lipophilic drugs, nanosuspension (NS) has been reported as one of the most promising techniques to improve the dissolution rate limited bioavailability of such drugs [22]. In general, bottom up and top down techniques are used to prepare NS [22,23]. In bottom up process, drug is added in solvent that dissolves it completely and then added to antisolvent by aid of stirring to form precipitates.…”
Section: Introductionmentioning
confidence: 99%
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