Nanotechnology and Its Potential Implications in Ovary Cancer

Jit, Bimal Prasad; Padhan, Biswajita; Sharma, Ashok

doi:10.1007/978-981-16-2516-9_10

Cited by 1 publication

(1 citation statement)

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“…For the past two decades, frontline treatment has included standalone chemotherapy or in combination with cytoreductive surgery (CRS) (Wang et al, 2020). In addition, adjuvant chemotherapy, maintenance chemotherapy, genetic counseling, nanoparticle-based therapy, and gene therapy are part of modern-day treatments (Jit et al, 2022). Due to adverse side effects and higher costs of drugs and treatments, synthetic drugs are falling out of treatment choice, especially in developing countries like India.…”

Section: Introductionmentioning

confidence: 99%

Comparison of in vitro antioxidant, antimicrobial and anticancer activity of Murraya koenigii leaf and stem extracts in ovarian cancer cells

Hajare

Patade

Shrimangale

et al. 2023

Preprint

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Ovarian cancer (OC) is the most lethal gynecological cancer, due to its diagnosis at later stages III and IV. Drug resistance developed at later stages further decreases survival rates to 30% in ovarian cancer patients. Natural compounds isolated from plant extract can have promising potential in cancer treatment due to their minimal side effects. Murraya koenigii (MK) leaves commonly used in Indian cuisines, are known to have antimicrobial, antifungal, and antioxidant activity. However, very few studies show the effect of MK extracts on ovarian cancer. This study shows the comparison of phytochemical content, antioxidant, antimicrobial and cytotoxic activities of methanol, aqueous and toluene extracts of MK leaves and stems. These extracts showed anticancer activity on the ovarian teratocarcinoma cell line - PA1 via apoptosis and antiangiogenic effect on healthy chick embryos.

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Section: Introductionmentioning

confidence: 99%