Nasal inflammation and personal exposure to fine particles PM2.5 in asthmatic children

Nikasinovic, Lydia; Just, Jocelyne; Sahraoui, F.; Seta, Nathalie; Grimfeld, A; Momas, Isabelle

doi:10.1016/j.jaci.2006.03.023

Cited by 85 publications

(50 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Some studies have found that subjects exposed to PM10 had more upper respiratory symptoms than those exposed to lower levels (683,684). PM2.5 can induce nasal eosinophilia (685). In developing countries, automobile pollution in large cities is becoming a major problem because of the increased traffic and the level of maintenance of vehicles which emit very large quantities of pollutants.…”

Section: Pollutantsmentioning

confidence: 99%

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008*

Bousquet¹,

Khaltaev²,

Cruz³

et al. 2008

Allergy

3,861

1,761

View full text Add to dashboard Cite

Section: Pollutantsmentioning

confidence: 99%

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008*

Bousquet¹,

Khaltaev²,

Cruz³

et al. 2008

Allergy

3,861

1,761

View full text Add to dashboard Cite

“…Figure 6. a) and b) The respective quality factor and filtration efficiency of electrospun (4,6,8,10, and 12 wt%) PAN membranes compared to a commercial glass-fiber filter (GF); c) filtration efficiency and pressure drop for different basis weights of 12 wt% PAN membranes and commercial GF filters at 300 nm particle size; d) the quality factor for different basis weight of 12 wt% PAN membranes and commercial GF filters.…”

Section: Filtration Efficiency Of the Aerosol Particlesmentioning

confidence: 99%

“…[3][4][5][6] Ultrafine particles smaller than 0.3 mm may occur in air streams from condensates in the form of metal dust fumes. Viruses are equally small and can represent a real challenge for separation due to the need for special properties such as, small fiber size, high specific surface area, and functionalized membrane surfaces.…”

Section: Introductionmentioning

confidence: 99%

High Efficiency Poly(acrylonitrile) Electrospun Nanofiber Membranes for Airborne Nanomaterials Filtration

et al. 2017

View full text Add to dashboard Cite

The potential of poly(acrylonitrile) electrospun membranes with tuneable pore size and fiber distributions were investigated for airborne fine-particle filtration for the first time. The impact of solution concentration on final membrane properties are evaluated for the purpose of designing separation materials with higher separation efficiency. The properties of fibers and membranes are investigated systematically: the average pore distribution, as characterized by capillary flow porometry, and thermo-mechanical properties of the mats are found to be dependent on fiber diameter and on specific electrospinning conditions. Filtration efficiency and pressure drop are calculated from measurement of penetration through the membranes using potassium chloride (KCl) aerosol particles ranging from 300 nm to 12 mm diameter. The PAN membranes exhibited separation efficiencies in the range of 73.8-99.78% and a typical quality factor 0.0224 (1 Pa À1 ) for 12 wt% PAN with nanofibers having a diameter of 858 nm. Concerning air flow rate, the quality factor and filtration efficiency of the electrospun membranes at higher face velocity are much more stable than for commercial membranes. The results suggest that the structure of electrospun membranes is the best for air filtration in terms of filtration stability at high air flow rate.

show abstract

“…However, it is often difficult to differentiate between acute, repeated acute (81) and chronic exposures such as outdoor air pollution which can induce nasal inflammation and symptoms in both adults and children (82)(83)(84)(85). More data are needed on a global scale to appreciate these effects.…”

Section: Phenotype Of Narmentioning

confidence: 99%

Important research questions in allergy and related diseases: nonallergic rhinitis: a GA²LEN paper

Bousquet

Fokkens

Burney

et al. 2008

Allergy

170

148

View full text Add to dashboard Cite

Important research questions in allergy and related diseases: nonallergic rhinitis: a GA 2 LEN paper Nonallergic rhinitis (NAR) can be defined as a chronic nasal inflammation which is not caused by systemic IgE-dependent mechanisms. It is common and probably affects far more than 200 million people worldwide. Both children and adults are affected. However, its exact prevalence is unknown and its phenotypes need to be evaluated using appropriate methods to better understand its pathophysiology, diagnosis and management. It is important to differentiate between infectious rhinitis, allergic/NAR and chronic rhinosinusitis, as management differs for each of these cases. Characterization of the phenotype, mechanisms and management of NAR represents one of the major unmet needs in allergic and nonallergic diseases. Studies on children and adults are required in order to appreciate the prevalence, phenotype, severity and co-morbidities of NAR. These studies should compare allergic and NAR and consider different age group populations including elderly subjects. Mechanistic studies should be carried out to better understand the disease(s) and risk factors and to guide towards an improved diagnosis and therapy. These studies need to take the heterogeneity of NAR into account. It is likely that neuronal mechanisms, T cells, innate immunity and possibly auto-immune responses all play a role in NAR and may also contribute to the symptoms of allergic rhinitis.

show abstract

Nasal inflammation and personal exposure to fine particles PM2.5 in asthmatic children

Cited by 85 publications

References 47 publications

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008*

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008*

High Efficiency Poly(acrylonitrile) Electrospun Nanofiber Membranes for Airborne Nanomaterials Filtration

Important research questions in allergy and related diseases: nonallergic rhinitis: a GA²LEN paper

Contact Info

Product

Resources

About

Nasal inflammation and personal exposure to fine particles PM2.5 in asthmatic children

Cited by 85 publications

References 47 publications

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008*

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008*

High Efficiency Poly(acrylonitrile) Electrospun Nanofiber Membranes for Airborne Nanomaterials Filtration

Important research questions in allergy and related diseases: nonallergic rhinitis: a GA2LEN paper

Contact Info

Product

Resources

About

Important research questions in allergy and related diseases: nonallergic rhinitis: a GA²LEN paper