Natural Rubber Latex Allergy

Brehler, Randolf; Kütting, Birgitta

doi:10.1001/archinte.161.8.1057

Cited by 39 publications

(4 citation statements)

References 100 publications

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“…Cross‐reactions in case of latex allergy may be to banana, avocado, kiwi, chestnut, papaya, figs. Even cross‐reactions to potato and tomato have been reported as well as cross‐reactions to Ficus benjamina (85). Cross‐reactivities occur when two or more allergens share epitopes, or in some cases have very similar epitopes, and therefore bind to the same IgE‐antibodies.…”

Section: Children Above 4 Yearsmentioning

confidence: 99%

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Allergy testing in children: why, who, when and how?

Høst

Andrae

Чаркин

et al. 2003

Allergy

178

103

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Section: Children Above 4 Yearsmentioning

confidence: 99%

Section: Children Above 4 Yearsmentioning

confidence: 99%

Allergy testing in children: why, who, when and how?

Høst

Andrae

Чаркин

et al. 2003

Allergy

178

103

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“…[28] Commonly known as silicone, PDMS is widely used for its biocompatibility, good chemical stability, ease of fabrication using injection molding or extrusion, and low cost. [29][30][31] Many implantable device makers have moved away from classical medical elastomers and plastics such as latex and polyvinyl chloride due to allergens [32] or plasticizers [33] in these materials that leach out and often lead to irritation or complications. PDMS-based devices do not require plasticizers and have been shown to lead to fewer complications than latex and polyurethane-based devices.…”

mentioning

confidence: 99%

A Readily Scalable, Clinically Demonstrated, Antibiofouling Zwitterionic Surface Treatment for Implantable Medical Devices

et al. 2022

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conditions to maintain the scale of medical device manufacturing; and 4) the treatment must not incorporate antibiotics to maintain global antimicrobial stewardship efforts. The zwitterionic polymer polysulfobetaine (PSB) was selected as the antifouling component of the surface modification to benefit from its biocompatibility, ultralow-fouling properties, and oxidative stability. By adsorbing water electrostatically, PSB coatings form a thin hydration barrier that prevents organic materials from adhering to surfaces. [22] Commonly used approaches to attach PSB coatings to surfaces, such as radical-initiated graft polymerizations of PSB-methacrylate necessitate the use of oxygen-free conditions, [23] preconditioning steps, [24] or long reaction times [25] that do not meet scalability requirements. To circumvent the use of air-free graft polymerizations, we employ perfluorophenylazide (PFPA) chemistry as a molecular anchor to link the PSB coatings onto the surfaces of polymeric materials under ambient conditions. When triggered with UV-light, PFPA moieties generate a highly reactive nitrene that forms covalent bonds with materials containing amines, CC double bonds, and CH bonds. [26,27] With this method, PSB is rapidly coated onto a broad range of substrates using UV light under ambient conditions with no preconditioning steps. Thus, many different medical devices may be quickly and conveniently treated on the manufacturing level.We first demonstrate the effect of the treatment on polydimethylsiloxane (PDMS) as an exemplary, extremely difficultto-modify model for a common elastomer used in implantable medical devices. [28] Commonly known as silicone, PDMS is widely used for its biocompatibility, good chemical stability, ease of fabrication using injection molding or extrusion, and low cost. [29][30][31] Many implantable device makers have moved away from classical medical elastomers and plastics such as latex and polyvinyl chloride due to allergens [32] or plasticizers [33] in these materials that leach out and often lead to irritation or complications. PDMS-based devices do not require plasticizers and have been shown to lead to fewer complications than latex and polyurethane-based devices. [34] Despite its ideal properties, the nonpolar nature of PDMS facilitates the adhesion of organic materials. Bacteria, platelets, proteins, and other biomolecules bind strongly to the hydrophobic surfaces of PDMS elastomers, leading to the colonization and proliferation of biofilms. [22] When common hydrophilic surface treatments are performed on PDMS, such as plasma oxidation, [35] UV-ozone, [36] or corona discharge, [37] the effects are short-term due to rapid hydrophobic recovery. The highly mobile chains of PDMS (glass transition temperature ≈ −120 °C) can reorient themselves to "hide" the surface modified elastomers, when exposed to air, within hours. [38] Other methods seeking long-lasting hydrophilic PDMS surfaces typically require preconditioning steps with silane [39][40][41] chemistry or radical polymerization. [...

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“…Despite being durable, waterproof, and elastic, latex DMGs have been held accountable for inducing some allergic reactions in 6% of the global users (Preece et al 2021 ). Hence, raising concerns over latex allergy among physicians and paramedics have prompted the use of non-latex DMGs such as nitrile and vinyl gloves (Brehler and Kütting 2001 ).…”

Section: Research Settingmentioning

confidence: 99%

Recycling COVID-19 health care wastes in bitumen modification: a case of disposable medical gloves

Gedik

Ozcan

Özcanan

2023

Environ Sci Pollut Res

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Disposable medical gloves (DMGs) have long been used to mitigate the risk of direct exposure to diverse microorganisms and body fluids; hence, they are a critical weapon to protect patients and healthcare staff from infectious diseases. Measures to control the spread of COVID-19 have sparked the production of an excessive number of DMGs, most of which are eventually being disposed of in landfills. Untreated DMGs in landfills do not only pose a direct risk of transmitting coronavirus and other pathological germs but also pollute air, water, and soil dramatically. As a healthier alternative, recycling discarded polymer-rich DMGs into bitumen modification is considered to be a prospective waste management strategy applicable to the asphalt pavement industry. In this study, this conjecture is tested by examining two common DMGs — latex gloves and vinyl gloves — at four different percentages (1%, 2%, 3%, and 4% by weight). The morphological characteristics of DMG-modified specimens were inspected by using a high-definition scanning electron microscope (SEM) equipped with an energy dispersive X-ray analyzer (EDX). A wide range of laboratory tests including penetration, softening point temperature, ductility, and elastic recovery were undertaken to evaluate the impact of waste gloves on the conventional engineering properties of bitumen. Moreover, viscoelastic behavior and modification processing were studied by conducting the dynamic shear rheometer (DSR) test and the Fourier transform infrared spectroscopy (FTIR) analysis. Test results have revealed the outstanding potential of recycled DMG waste for modifying neat asphalt binder. More specifically, bitumens modified with 4% latex glove and 3% vinyl glove were seen as capable of superiorly withstanding permanent deformations caused by heavy axle loads at high service temperatures. Furthermore, it has been shown that 1.2 tons of modified binder would embed approximately 4000 pairs of recycled DMGs. This study shows that DMG waste can be used as a viable modifier, which would help open a new avenue for mitigating the environmental pollution arising from the COVID-19 pandemic. Graphical Abstract

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Natural Rubber Latex Allergy

Cited by 39 publications

References 100 publications

Allergy testing in children: why, who, when and how?

Allergy testing in children: why, who, when and how?

A Readily Scalable, Clinically Demonstrated, Antibiofouling Zwitterionic Surface Treatment for Implantable Medical Devices

Recycling COVID-19 health care wastes in bitumen modification: a case of disposable medical gloves

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