Natural β-chitin-protein complex film obtained from waste razor shells for transdermal capsaicin carrier

Abstract

In the literature, the produced β-chitin samples are in powder or flake forms but there is no natural β-chitin based film. Also, the commercially available transdermal patches are produced from synthetic polymers. In this regard, we produced natural β-chitin-protein complex (CPC) film from the waste shells of Ensis spp. The obtained natural film was characterized by FTIR, TGA and SEM. Additionally, swelling, thickness, contact angle and antioxidant tests were done to learn more about the films. After production and characterization of the film, capsaicin, which is commonly used for pain relief was loaded into the film. The loading capacity was recorded as 5.79%. The kinetic models were studied in three different pH, then the results were fitted with Higuchi model with high correlation at pH 7.4. After considering all the obtained results, the capsaicin loaded CPC film may be an alternative candidate for transdermal patch instead of the synthetic ones.

Production of natural chitin film from pupal shell of moth: Fabrication of plasmonic surfaces for SERS-based sensing applications

“…Hydrophobicity is a desirable feature for many industrial applications. The dorsal dark area of the natural chitin film herein shows higher hydrophobicity than chitin film structures obtained from other organisms (Aylanc et al, 2020;Kaya et al, 2018;Kaya, Sargin et al, 2017). In view of these results, natural chitin film may be used for industrial applications requiring hydrophobic surfaces.…”

Revamping squid gladii to biodegradable composites: In situ grafting of polyaniline to β-chitin and their antibacterial activity

“…It is said that a degradation temperature in the window 250 to 350°C is a distinct characteristic of chitin in β-form. 29 The third stage occurred in the range of 400 to 600°C is attributed to thermal degradation of pyranose ring and the decomposition of the residual carbon. DSC gave similar thermal profiles for β-chitin, PANI and β-chitin-g-PANI as that of TGA.…”

β‐Chitin and chitosan from waste shells of edible mollusks as a functional ingredient

“…The loss that occurs in the first step can be attributed to the water molecules during evaporation in the chitin and chitosan molecules, and the loss that occurs in the second step can be attributed to the degradation of chitin and chitosan (Ofem, 2015). The first loss of the chitin and chitosan from different mollusk shells ranged from 5% to 9.61%, whereas the second mass loss ranged from 51.9% to 63.5% (Aylanc et al, 2020;Cabrera-Barjas et al, 2021;Huang & Tsai, 2020;Ianiro et al, 2014;Kaya et al, 2016;Mohan et al, 2019;Varma et al 2021). The maximum temperatures (DTG max) for the degradation of chitin and chitosan from several mollusk shells ranged from 380 to 444 • C (Mohan et al, 2019;Rajathy et al, 2021).…”

“…Meanwhile, the structural and functional properties of chitin and its derivatives from various mollusk shells have been reported earlier (Akpan et al, 2018;Aylanc et al, 2020;Cabrera-Barjas et al, 2021;Hazeena et al, 2022;Mohan et al, 2019;Nouj et al, 2022). However, no comprehensive review were focused on the edible mollusk shell waste derived chitin and chitosan.…”