Nause and vomiting in pregnancy

Fairweather, D. V. I.

doi:10.1016/0002-9378(68)90445-6

Cited by 313 publications

(109 citation statements)

References 122 publications

Supporting

Mentioning

101

Contrasting

Unclassified

Order By: Relevance

“…Hyperemesis gravidarum (HG), characterised by extreme nausea and vomiting in early pregnancy,12 is associated with gestational hypertension, pre‐eclampsia as well as placental abruption 13. The prevalence of HG varies between 0.3 and 3.2%, depending on the maternal country of birth 14, 15.…”

Section: Introductionmentioning

confidence: 99%

Hyperemesis gravidarum and long‐term mortality: a population‐based cohort study

Fossum

Vikanes

Næss

et al. 2016

BJOG

View full text Add to dashboard Cite

ObjectiveTo investigate whether exposure to hyperemesis gravidarum (HG) is associated with increased maternal long‐term mortality.DesignPopulation‐based cohort study.SettingMedical Birth Registry of Norway (1967–2002) linked to the Cause of Death Registry.PopulationWomen in Norway with singleton births in the period 1967–2002, with and without HG. Women were followed until 2009 or death.MethodsCox proportional hazard regression model was applied to estimate hazard ratios (HRs) with 95% confidence interval (CI).Main outcome measuresThe primary outcome was all‐cause mortality during follow up. Secondary outcomes were cause‐specific mortality (cardiovascular mortality, deaths due to cancer, external causes or mental and behavioural disorders).ResultsOf 999 161 women with singleton births, 13 397 (1.3%) experienced HG. During a median follow up of 26 years (25 902 036 person‐years), 43 470 women died (4.4%). Women exposed to HG had a lower risk of long‐term all‐cause mortality compared with women without HG (crude HR 0.82; 95% CI 0.75–0.90). When adjusting for confounders, this reduction was no longer significant (adjusted HR 0.92; 95% CI 0.84–1.01). Women exposed to HG had a similar risk of cardiovascular death as women not exposed (adjusted HR 1.04; 95% CI 0.83–1.29), but a lower long‐term risk of death from cancer (adjusted HR 0.86; 95% CI 0.75–0.98).ConclusionIn this large population‐based cohort study, HG was not associated with an increased risk of long‐term all‐cause mortality. Women exposed to HG had no increase in mortality due to cardiovascular disease, but had a reduced risk of death from cancer.Tweetable abstractPopulation‐based cohort study: Hyperemesis was not associated with an increased risk of long‐term mortality.

show abstract

Section: Introductionmentioning

confidence: 99%

Hyperemesis gravidarum and long‐term mortality: a population‐based cohort study

Fossum

Vikanes

Næss

et al. 2016

BJOG

View full text Add to dashboard Cite

show abstract

“…Hyperemesis gravidarum (HG) occurs in 1 to 2% of pregnancies, 1,2 and is the most clinically severe manifestation of nausea and vomiting of pregnancy (NVP). It causes weight loss during pregnancy, [3][4][5][6] dehydration, electrolyte disturbance 7 and nutritional deficiency, which in many cases can necessitate the use of intravenous hydration therapy or parenteral nutrition.…”

Section: Introductionmentioning

confidence: 99%

The psychosocial burden of hyperemesis gravidarum

et al. 2007

View full text Add to dashboard Cite

Objective: To describe the psychosocial burden of hyperemesis gravidarum (HG) in a large cohort of affected women, focusing on previously unreported problems. Result: Of the 808 participants, 626 (77.5%) were American. A large majority (82.8%) reported that HG caused negative psychosocial changes, consisting of (1) socioeconomic changes, for example, job loss or difficulties, (2) attitude changes including fear regarding future pregnancies and (3) psychiatric sequelae, for example, feelings of depression and anxiety, which for some continued postpartum. Women who reported that their health-care provider was uncaring or unaware of the severity of their symptoms were nearly twice as likely to report these psychiatric sequelae (odds ratio 1.86, 95% confidence interval 1.06 to 3.29, P ¼ 0.032).Conclusion: Over 80% of a large cohort of women with HG reported that HG caused a negative psychosocial impact.

show abstract

“…Hyperemesis gravidarum (HG) is defined as intractable nausea and vomiting during pregnancy that often leads to fluid and electrolyte imbalance, weight loss of 5% or greater, and nutritional deficiency requiring hospital admission [1] . The incidence of HG varies from 0.3%-2% of all live births [2] .…”

Section: Hyperemesis Gravidarummentioning

confidence: 99%

Liver Disease in Pregnancy

Lee¹,

Koh²

1988

Yeungnam Univ J Med

View full text Add to dashboard Cite

Liver diseases in pregnancy may be categorized into liver disorders that occur only in the setting of pregnancy and liver diseases that occur coincidentally with pregnancy. Hyperemesis gravidarum, preeclampsia/eclampsia, syndrome of hemolysis, elevated liver tests and low platelets (HELLP), acute fatty liver of pregnancy, and intrahepatic cholestasis of pregnancy are pregnancy-specific disorders that may cause elevations in liver tests and hepatic dysfunction. Chronic liver diseases, including cholestatic liver disease, autoimmune hepatitis, Wilson disease, and viral hepatitis may also be seen in pregnancy. Management of liver disease in pregnancy requires collaboration between obstetricians and gastroenterologists/hepatologists. Treatment of pregnancy-specific liver disorders usually involves delivery of the fetus and supportive care, whereas management of chronic liver disease in pregnancy is directed toward optimizing control of the liver disorder. Cirrhosis in the setting of pregnancy is less commonly observed but offers unique challenges for patients and practitioners. This article reviews the epidemiology, pathophysiology, diagnosis, and management of liver diseases seen in pregnancy.

show abstract

Nause and vomiting in pregnancy

Cited by 313 publications

References 122 publications

Hyperemesis gravidarum and long‐term mortality: a population‐based cohort study

Hyperemesis gravidarum and long‐term mortality: a population‐based cohort study

The psychosocial burden of hyperemesis gravidarum

Liver Disease in Pregnancy

Contact Info

Product

Resources

About