Necrotizing Fasciitis

Fugitt, J. Brett; Puckett, Michael L.; Quigley, Michael; Kerr, Stewart M.

doi:10.1148/rg.245035169

Cited by 88 publications

(57 citation statements)

References 9 publications

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“…Radiographic studies must be undertaken to detect air in soft tissues. When the patient is seriously ill, Fugitt et al pointed out, necrotizing fasciitis is a surgical emergency with high mortality; therefore, imaging studies should not delay surgical intervention (6).…”

Section: Pathophysiologymentioning

confidence: 99%

Modern Concepts of the Diagnosis and Treatment of Necrotizing Fasciitis

Edlich

Cross

Dahlstrom

et al. 2010

The Journal of Emergency Medicine

106

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Section: Pathophysiologymentioning

confidence: 99%

Modern Concepts of the Diagnosis and Treatment of Necrotizing Fasciitis

Edlich

Cross

Dahlstrom

et al. 2010

The Journal of Emergency Medicine

106

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“…This phenomenon was described by Weiss and Laverdiere in 1997 [10]. Gas on plain radiographs is a more inconsistent sign [10,11].…”

Section: Discussionmentioning

confidence: 92%

“…However, mortality associated with necrotizing fasciitis is still high. It has a reported cumulative mortality rate of 34% (range 6% to 76%) with death due to sepsis, respiratory failure, kidney failure, or multiorgan system failure [11,13].…”

Section: Discussionmentioning

confidence: 99%

Necrotizing fasciitis with fatal outcome: a report of two cases

Heinze

Püschel

Tsokos

2010

Forensic Sci Med Pathol

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Two cases of sudden and unexpected death due to necrotizing fasciitis are presented with a short overview of this rare disease with special reference to pathological features and causative and epidemiological factors. One case occurred as a complication of liposuction surgery, and the second presented after minor trauma. Based on the autopsy findings and an interdisciplinary approach, medico-legal evaluation provides a substantial basis for later court hearings in such cases.

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“…Key findings are thickened and distorted fascial planes with fluid accumulation in fascia and subcutaneous edema. Furthermore, similar to CT scan, detection of gas is of high diagnostic value in ultrasound scan (15). Surgical debridement of infected tissue within the 1st day of infection is the cornerstone of therapy (7).…”

Section: Discussionmentioning

confidence: 99%

Skin and Soft Tissue Infection as a Complication of Varicella Infection Ended up in Using Intravenous Immunoglobulin Instead of Surgical Debridement: A Case Report and Short Review of Literature

Emami

Mirmohamadi

Esfehani

2017

Arch Clin Infect Dis

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Introduction: Varicella infection is a vaccine-preventable infection, which can result in different complications. Necrotizing fasciitis (NF) as a skin and soft tissue infection is a rare complication of varicella infection in childhood. Early diagnosis and treatment of necrotizing fasciitis can save life. Surgical debridement along with appropriate antimicrobial treatment is very common. However, some patients cannot undergo surgeries and physicians should try other options. Case Presentation: A 6-year-old male with a history of chicken pox infection was admitted due to abdominal pain and fever. On physical examination, abdominal tenderness and diffused erythema on the entire abdomen as well as crepitation was prominent. As acute abdomen was ruled out by abdominal sonography, the patient received antimicrobial treatment, which was ineffective. Meanwhile, his hemodynamic condition worsened and sign of scaly skin presented, antimicrobial regimen was changed and surgical consultation was ordered. Unfortunately, surgical debridement was impossible due to extensive tissue involvement. Intravenous immunoglobulin (IVIG) was initiated and patient was transferred to the intensive care unit (ICU). Within 72 hours of administering IVIG, skin erythema and abdominal pain decreased and on the 10th day of admission, the patient became afebrile and healthy. Antibiotics were discontinued on the 12th day and the patient was discharged in good conditions. Conclusions: Although tissue debridement is the cornerstone to treat necrotizing tissue infection, in some cases patients might benefit from adjuvant treatments such as IVIG. Although this treatment cannot be generalized to every patient, it may be concluded that physicians can save surgical options and try IVIG under close clinical observation to avoid possible multiple surgical debridement.

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Necrotizing Fasciitis

Cited by 88 publications

References 9 publications

Modern Concepts of the Diagnosis and Treatment of Necrotizing Fasciitis

Modern Concepts of the Diagnosis and Treatment of Necrotizing Fasciitis

Necrotizing fasciitis with fatal outcome: a report of two cases

Skin and Soft Tissue Infection as a Complication of Varicella Infection Ended up in Using Intravenous Immunoglobulin Instead of Surgical Debridement: A Case Report and Short Review of Literature

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