Necrotizing Pneumonia In Children: A Review

Teresinha Mocelin, Helena; Bueno Fischer, Gilberto; Danezi Piccini, Júlia; de Oliveira Espinel, Júlio; Feijó Andrade, Cristiano; Bush, Andrew

doi:10.1016/j.prrv.2024.02.003

Paediatric Respiratory Reviews

2024

DOI: 10.1016/j.prrv.2024.02.003

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Necrotizing Pneumonia In Children: A Review

Helena Teresinha Mocelin,

Gilberto Bueno Fischer,

Júlia Danezi Piccini

et al.

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2024

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Cited by 2 publications

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Pneumococci remain the main cause of complicated pediatric pneumonia in the post-pandemic era despite extensive pneumococcal vaccine use

Gomes-Silva,

Pinho,

Friães

et al. 2024

Pneumonia

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Nucleic acid amplification tests (NAATs) greatly enhance the capacity to identify the etiology of pediatric complicated pneumonia. However, the use of pneumococcal conjugate vaccines could reduce the importance of Streptococcus pneumoniae in pediatric complicated pneumonia with the potential emergence of other bacterial agents. Using an expanded NAAT in culture negative pleural fluid or empyema samples collected in 2010–2024 (n = 554) in Portugal, we show that S. pneumoniae remains the most frequent agent despite decades of pneumococcal conjugate vaccine use and the COVID-19 pandemic. A rebound in pediatric complicated pneumonia occurred post-pandemic, including a rise in cases by Streptococcus pyogenes and Haemophilus influenzae. Empiric therapy of pediatric complicated pneumonia should still consider S. pneumoniae as the most likely cause, even in countries where the pneumococcal conjugate vaccine is in the national immunization program with a high uptake.

show abstract

Pneumococci remain the main cause of complicated pediatric pneumonia in the post-pandemic era despite extensive pneumococcal vaccine use

Gomes-Silva,

Pinho,

Friães

et al. 2024

Pneumonia

View full text Add to dashboard Cite

show abstract

Tratamento da pneumonia necrosante na pediatria: revisão de literatura

Guida,

Barros,

Fernandes

et al. 2024

Cuad. Ed. Desar.

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Necrotizing Pneumonia In Children: A Review

Cited by 2 publications

References 36 publications

Pneumococci remain the main cause of complicated pediatric pneumonia in the post-pandemic era despite extensive pneumococcal vaccine use

Pneumococci remain the main cause of complicated pediatric pneumonia in the post-pandemic era despite extensive pneumococcal vaccine use

Tratamento da pneumonia necrosante na pediatria: revisão de literatura

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