Necrotizing Sarcoid Granulomatosis

Llopart, L.; López, B. Barreiro; Guiuc, Pilar Forcada

doi:10.1016/s1579-2129(06)60238-3

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“… a Results based on available data in 130 patients with NSG reported in the literature . Cases of sarcoidosis showing histologic features of necrosis, like in the study of Hsu et al, are not included as NSG in the current study, as opposed to a previous one .…”

Section: Introductionmentioning

confidence: 99%

Necrotizing sarcoid granulomatosis: A distinctive form of pulmonary granulomatous disease

Karpathiou

Batistatou

Boglou

et al. 2017

Clinical Respiratory J

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Section: Introductionmentioning

confidence: 99%

Necrotizing sarcoid granulomatosis: A distinctive form of pulmonary granulomatous disease

Karpathiou

Batistatou

Boglou

et al. 2017

Clinical Respiratory J

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Necrotizing Sarcoid Granulomatosis in a Family of Patients with Sarcoidosis Reinforces the Association between Both Entities

Lazzarini¹,

Teixeira²,

Rodrigues³

et al. 2007

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Necrotizing sarcoid granulomatosis (NSG) is a rare entity mainly characterized by a prominent granulomatous vasculitis affecting middle-aged or old individuals and with a favorable prognosis. Although many believe it is a variant of sarcoidosis, the proper classification is still a matter of debate as some of its features are found in sarcoidosis but also in Churg-Strauss syndrome, Wegener’s disease and hypersensitivity pneumonitis. In this paper, we described for the first time a case of NSG in a family with several cases of sarcoidosis, reinforcing the relationship between NSG and sarcoidosis. Additional interesting findings were the young age of the patient (15 years old), the symptoms limited to the respiratory tract (uncommon when NSG affects youngsters) and the increase in serologic markers of autoimmune disease. Though complete criteria for autoimmune disease were not present, systemic lupus erythematosus and Sjögren’s syndrome are possible candidates. As sarcoidosis is described to be associated with several autoimmune diseases, this finding is an additional suggestion of the relationship between both entities.

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Necrotizing Sarcoid Granulomatosis

Cited by 2 publications

References 5 publications

Necrotizing sarcoid granulomatosis: A distinctive form of pulmonary granulomatous disease

Necrotizing sarcoid granulomatosis: A distinctive form of pulmonary granulomatous disease

Necrotizing Sarcoid Granulomatosis in a Family of Patients with Sarcoidosis Reinforces the Association between Both Entities

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