Necrotizing soft-tissue infections: our experience at rural tertiary care centre

Determinants of Mortality in Necrotizing Soft Tissue Infections

“…Among them age (more than 60 years), intravenous drug abuse, diabetes, obesity, malnutrition, congestive heart disease, chronic pulmonary disease, peripheral vascular disease, chronic alcoholism, immunocompromised states such as malignancy, steroid use, transplantation, and human immunodeficiency virus infection are the most commonly cited [5][6][7][8][9][10][11][12][13]. Despite encountering NSTI fairly commonly, we could identify only 8 series from India from the year 2000 onwards [6][7][8][9][10][11][12][13]. Of these, one exclusively dealt with upper limb NSTI occurring in diabetic patients [6], while the others were more inclusive.…”

“…The overall mortality in these studies ranged from as low as 1.85% to as high as 27%. Higher mortality was seen in patients aged more than 50 years, those with shock, diabetes mellitus, leucocytosis, jaundice, hyponatremia, hypoalbuminemia, anaemia, elevated serum creatinine, higher percentage of body surface area involved and delay in surgery [7][8][9][10][11][12][13].…”