Needle Biopsy in Children With Liver Diseases

Pietrobattista, Andrea; Alterio, Arianna; Natali, Giuseppe Di; Fruhwirth, Rodolfo; Comparcola, Donatella; Sartorelli, Maria Rita; Nobili, Valério

doi:10.5772/19383

Cited by 5 publications

(3 citation statements)

References 43 publications

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“…(63,74). If the PT is prolonged by 4 seconds or more, equivalent to INR >1.5, then strategies to ameliorate coagulopathy should be deployed (74,76,127,128). If patients show abnormalities of the coagulation cascade, support with vitamin K and with transfusions of FFP or platelets may be required.…”

Section: Recommended Protocol and Checklistmentioning

confidence: 99%

“…Bleeding time determination could be considered if platelet dysfunction is suspected. In most cases PT/INR and platelet count should be checked within the 24 hours previous to the LB (63,74). If the PT is prolonged by 4 seconds or more, equivalent to INR >1.5, then strategies to ameliorate coagulopathy should be deployed (74,76,127,128). If patients show abnormalities of the coagulation cascade, support with vitamin K and with transfusions of FFP or platelets may be required.…”

Section: Recommended Protocol and Checklistmentioning

confidence: 99%

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Liver Biopsy in Children

Dezsőfi

Baumann²,

Dhawan

et al. 2015

J. pediatr. gastroenterol. nutr.

179

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Liver biopsy (LB) is still the criterion standard procedure for obtaining liver tissue for histopathological examination and a valuable tool in the diagnosis, prognosis, and management of many parenchymal liver diseases. The aim of this position paper is to summarise the present practice of paediatric LB and make recommendations about its performance. Although histological evaluation of the liver is important in assessing prognosis and exploring treatment, noninvasive techniques (ie, imaging, laboratory markers) may replace use of liver histology. The indications for LB are changing as present knowledge of aetiologies, pathomechanism, and therapeutic options in paediatric liver disease is evolving. Adult and paediatric literature was reviewed to assess the existing clinical practice of LB with focus on the technique, indications, risk of complications, and contraindications in paediatrics. This position paper presents types of LB, indications, complications, contraindications, and an essential checklist for paediatric LB.

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Section: Recommended Protocol and Checklistmentioning

confidence: 99%

Section: Recommended Protocol and Checklistmentioning

confidence: 99%

Liver Biopsy in Children

Dezsőfi

Baumann²,

Dhawan

et al. 2015

J. pediatr. gastroenterol. nutr.

179

View full text Add to dashboard Cite

show abstract

“…Пункционная биопсия печени -быстрый и относи-тельно несложный с технической точки зрения способ получения образца ткани, имеющий в то же время ряд существенных потенциальных недостатков, таких как высокий риск развития осложнений (внутрибрюшное и внутрипеченочное кровотечение, пневмо-и гемото-ракс, желчный перитонит) и малый размер получаемо-го гепатобиоптата [17][18][19]. Пункционная биопсия пече-ни выполняется с помощью аспирационных (Menghini, Jamshidi, Klatskin) и режущих (Tru-cut, Vim-Silverman) игл.…”

Section: методы биопсии печени пункционная биопсияunclassified

Modern Possibilities of Endosurgical Biopsy in Children with Chronic Liver Diseases

et al. 2018

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Ultrasonic Characteristics of the Structure of the Liver Capsule in Healthy Children of Different Ages

Khrolenko

Dvoryakovsky

Dyakonova

et al. 2019

RPJ

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Ultrasound examination (ultrasound) takes the first place first among visual methods for analyzing the state of the liver parenchyma. Despite the improvement of ultrasound technology, it does not provide the necessary diagnostic accuracy in determining the stages of liver fibrosis. In this regard, it is necessary to search for additional diagnostic criteria to judge the state of the liver tissue and its superficial structures, primarily liver capsules.Materials and methods: the state of the liver capsule was assessed in 73 children of four age groups (2-18 years) without pathological changes in the hepatobiliary system, which were performed by ultrasound of the abdominal organs during preventive examinations. The structure of the capsule of the liver and visceral peritoneum was evaluated. Results. Direct dependence of the thickness of the liver capsule on the age of children was established (rs = 0.577, p = 0.0000). The capsule and visceral peritoneum represented a single and even echogenic structure (95.9%). Stratification of the leaves was detected in 8 children. A change in the shape of the edge of the right lobe of the liver was observed in 4 children. An increase in the severity of subcapsular blood flow in the liver was not detected in any healthy child.

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Needle Biopsy in Children With Liver Diseases

Cited by 5 publications

References 43 publications

Liver Biopsy in Children

Liver Biopsy in Children

Modern Possibilities of Endosurgical Biopsy in Children with Chronic Liver Diseases

Ultrasonic Characteristics of the Structure of the Liver Capsule in Healthy Children of Different Ages

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