Negative pressure wound therapy for skin grafts and surgical wounds healing by primary intention

Webster, Joan; Scuffham, Paul Anthony; Sherriff, Karen L; Stankiewicz, Monica; Chaboyer, Wendy

doi:10.1002/14651858.cd009261.pub2

Cited by 76 publications

(56 citation statements)

References 47 publications

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“…1,2 The rate of surgical site infection after cesarean delivery is between 3 and 18% 3-7 and may be as high as 30% in patients with body mass indexes (BMIs, calculated as weight (kg)/[height (m)] 2 ) of 50 or higher. 12 The benefits of negative pressure wound therapy 12 18 and surgical wounds expected to heal by primary intention. 9,10 As a result of the morbidity, mortality, and costs associated with surgical site infection, the Centers for Disease Control and Prevention developed guidelines for preventing infections including: appropriate selection and timing of prophylactic antibiotics, optimizing preoperative skin hygiene, and surgical skin preparation.…”

Section: Methodsmentioning

confidence: 99%

Prophylactic Use of Negative Pressure Wound Therapy After Cesarean Delivery

Echebiri

McDoom

Aalto

et al. 2015

Obstetrics &Amp; Gynecology

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Section: Methodsmentioning

confidence: 99%

Prophylactic Use of Negative Pressure Wound Therapy After Cesarean Delivery

Echebiri

McDoom

Aalto

et al. 2015

Obstetrics &Amp; Gynecology

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“…Another reason lies the pressure not being evenly controlled, which is likely to affect the venous return of the limb. Webster et al (17) confirmed that VSD reduces the transplantation failure rate. Although the daily cost of VSD is higher, VSD reduces dressing requirements and promotes wound healing and thus reduces hospitalization time (18).…”

Section: Discussionmentioning

confidence: 95%

Free dermatoplasty combined with vacuum sealing drainage for the treatment of large-area soft tissue defects accompanied by bone exposure in the lower leg

Yan

Wang

et al. 2013

Experimental and Therapeutic Medicine

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The aim of this study was to investigate the clinical efficacy of free dermatoplasty combined with vacuum sealing drainage (VSD) for the treatment of large-area soft tissue defects accompanied by bone exposure in the lower leg (crus). Free dermatoplasty combined with VSD was used to treat 36 patients with large-area soft tissue defects accompanied by bone exposure in the lower leg. The areas of the soft tissue defects ranged from 25×12 to 35×30 cm and the areas of exposed bone ranged from 6×4 to 10×6 cm. When evaluated by the open fracture Gustilo classification, 14 cases were of Gustilo type IIIA and 22 cases were of type IIIB. During surgery, adjacent available muscle flaps were transferred to cover the outer areas of the exposed bone and reduce the bone exposure range. Following VSD treatment, granulation tissues grew well and free dermatoplasty combined with VSD was used to treat and repair the wound surfaces. The patients were followed up for 1–5 years (mean duration, 2.5 years). All 36 cases with skin flap grafts survived, the free skin graft texture on the wound surface was good, the recovery of lower limb function was satisfactory and the success rate was 80.56%. Free dermatoplasty combined with VSD used for the treatment of large-area soft tissue defects accompanied by bone exposure in the lower leg may eliminate the need for amputation and complex surgery, and is a simple, fast and effective treatment method.

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“…However, there are several randomised trials and meta-analyses, which have assessed the effectiveness of NPWT for skin grafts and surgical wound healing by primary and secondary intentions and in chronic wounds compared with several conventional treatment methods. With regards to healing of surgical wound by primary intention, the evidence for the effect of NPWT for reducing surgical site infections, time to complete healing and wound dehiscence remains unclear[52]. A Cochrane Database Systematic Review assessed the effect of NPWT for the treatment of chronic wounds in comparison with five different comparators, which did not show that NPWT significantly increased the healing rate.…”

Section: Discussionmentioning

confidence: 99%

Systematic review of the negative pressure wound therapy in kidney transplant recipients

Shrestha¹

2016

WJT

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AIMTo review negative pressure wound therapy (NPWT) as an important addition to the conventional methods of wound management.METHODSA systematic review, performed by searching the PubMed, EMBASE and Cochrane Library databases, showed 11 case reports comprising a total of 22 kidney transplantation (KT) patients (range, 1 to 9), who were treated with NPWT. Application of NPWT was associated with successful healing of wounds, leg ulcer, lymphocele and urine leak from ileal conduit.RESULTSNo complications related to NPWT were reported. However, there was paucity of robust data on the effectiveness of NPWT in KT recipients; therefore, prospective studies assessing its safety and efficacy of NPWT and randomised trials comparing the effectiveness of NPWT with alternative modalities of wound management in KT recipients is recommended.CONCLUSIONNegative pressure incision management system, NPWT with instillation and endoscopic vacuum-assisted closure system are in investigational stage.

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Negative pressure wound therapy for skin grafts and surgical wounds healing by primary intention

Cited by 76 publications

References 47 publications

Prophylactic Use of Negative Pressure Wound Therapy After Cesarean Delivery

Prophylactic Use of Negative Pressure Wound Therapy After Cesarean Delivery

Free dermatoplasty combined with vacuum sealing drainage for the treatment of large-area soft tissue defects accompanied by bone exposure in the lower leg

Systematic review of the negative pressure wound therapy in kidney transplant recipients

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