Neodymium Catalyst for the Polymerization of Dienes and Polar Vinyl Monomers

Abstract

Ziegler-Natta catalysts have played a major role in industry for the polymerization of dienes and vinyl monomers. However, due to the deactivation of the catalyst, this system fails to polymerize polar vinyl monomers such as vinyl acetate, methyl methacrylate, and methyl acrylate. Herein, a catalytic system composed of NdCl ⋅3TEP/TIBA is reported, which promotes a quasi-living polymerization of dienes and is also active for the homopolymerization of polar vinyl monomers. Additionally, this catalytic system generates polymyrcene-b-polyisoprene and poly(myrcene)-b-poly(methyl methacrylate) diblock copolymers by sequential monomer addition. To encourage the replacement of petroleum-based polymers by environmentally benign biobased polymers, polymerization of β-myrcene is demonstrated with a catalytic activity of ≈106 kg polymer mol Nd h .

Halide-free neodymium phosphate based catalyst for highly cis-1,4 selective polymerization of dienes

“…This crystal structure has been reported previously. 14,26,27 However, it is worth noting that the reported methods were focused only on growing single crystals for spatial structural analysis. In contrast, our method can easily synthesize the neodymium catalyst in a preparative quantity and high purity.…”

“…In many cases, the halides are present in the catalyst itself, resulting in a binary system (along with the alkylaluminum cocatalyst). These catalysts contain electron donor ligands such as isopropanol, 12 tributyl phosphate, 13 triethyl phosphate, 14,15 and tetrahydrofuran (THF). 16 In other cases, the catalysts do not have any halide atoms coordinated to the metal and require an additional halide source, such as AlEt 2 Cl, forming a ternary catalytic system.…”

Histone Deacetylase Inhibitor (HDACi) Conjugated Polycaprolactone for Combination Cancer Therapy

“…By comparison of the 1 H NMR spectra, we confirmed the formation of the butyrolactone analogue during the polymerization (Figure 1). With the goal of obtaining the homopolymer in high yields we carried out the polymerization with a catalytic system introduced by our group, NdCl 3 ·3TEP/TIBA, 24 which produced the homopolymer with only <20 mol % transesterified product (Table 1 and Figure 1). With Sn(Oct) 2 and Zn(Undec) 2 , transesterification is more facilitated due to the higher temperatures employed (110 °C).…”

“…4-Hydroxycyclohexanone and NdCl 3 ·3TEP catalyst were synthesized according to previously published procedures. 24,25 …”

“…24 The synthesized homopolymer was employed to prepare nanoparticles (NP) with PEG surfactant to encapsulate DOX. The formed empty and DOX-loaded NPs were then analyzed to determine the size, morphology, drug release behavior, cytotoxicity, and cellular uptake in HeLa cells (Scheme 1).…”