Neonatal color Doppler US study: Normal values of cerebral blood flow velocities in preterm infants in the first month of life

Tracheal suctioning is associated with prolonged disturbances of cerebral hemodynamics in very low birth weight infants

“…Based on our model, a 10 mm Hg increase in PaCO 2 would increase mean CBFv by 2.90 cm s À1 ; this represents an approximately 15 to 25% increase in mean CBFv (based on resting measurements of middle cerebral artery mCBFv in premature infants with similar gestational ages during the first week of life). 31 The pattern and duration of change of mean CBFv following tracheal suctioning most closely mirrored the changes in PaCO 2 ; this corroborates our previous observations following surfactant administration that changes in mean CBFv were highly associated with changes in PaCO 2 . 19 Our results also agree with Skov et al 11 who observed in more mature and larger infants that changes in cerebral blood volume following tracheal suctioning were predominantly related to changes in PaCO 2 and not due to changes in MABP or oxygenation.…”

Ultrasound Diagnosis of Congenital Brain Anomalies

“…Knowledge of normal values of cerebral blood flow velocities and Doppler indices in neonates different gestation age is important for the monitoring maturational processes and growth of the immature brain and also useful for differential diagnosis of congenital and acquired CNS anomalies in both preterm and full-term neonates (Chavhan et al, 2008;). Normal neonatal values and postnatal changes of cerebral blood flow velocities have been reported by several examiners (Deeg & Rupprecht 1989;Romagnol et al, 2006;Vasiljevic et al, 2010). Table 2.…”

“…Every major vessel in the human body has a characteristic flow pattern that is visible in spectral waveforms obtained in that vessel with Doppler US. Familiarity with the Doppler waveforms characteristic of cerebral arteries and veins in neonates is important for accurate diagnosis of brain abnormalities ( The wave forms may be affected by age-and development-related hemodynamic differences (Chavhan et al, 2008, Romagnol et al, 2006. Values of cerebral blood flow velocities progressive increase with gestation age on consequence of progressive increase cardiac output, blood pressure and closing ductus arterosus (Vasiljevic et al, 2010).…”

Monitoring the Neonate: Basic Science

“…Ultrasound measures of middle cerebral artery blood fl ow are useful for detection of severe cerebral hypoperfusion in infants at risk for hypotension or large ductal shunts, as retrograde or poor diastolic fl ow is seen in the large arteries near the circle of Willis in these cases [ 74 ]. Normative data for cerebral blood fl ow velocity in "healthy" preterm neonates has been published [ 75 ]. In non-hypotensive neonates, both systolic and diastolic cerebral blood fl ow velocity increases as a function of postnatal and post-conceptual age [ 75 ].…”

“…Normative data for cerebral blood fl ow velocity in "healthy" preterm neonates has been published [ 75 ]. In non-hypotensive neonates, both systolic and diastolic cerebral blood fl ow velocity increases as a function of postnatal and post-conceptual age [ 75 ].…”