Neonatal Herpes Simplex and Incontinentia Pigmenti

Therapy resistant neonatal seizures, linear vesicular rash, and unusually early neuroradiological changes: incontinentia pigmenti

“…Therefore, in the presence of a vesicular exanthema following the lines of Blaschko, persisting seizures, and excluded infection, a high index of suspicion is needed. Noteworthy are two previous reports showing coexistence of IP and neonatal HSV infection [11,44]. Diagnosis is be confirmed by pathognomonic histology.…”