Neonatal outcomes according to different therapies for gestational diabetes mellitus

Silva, Amanda L. da; Amaral, Augusto Radünz do; Oliveira, Daniela Sousa; Martins, Lisiane; Silva, Mariana R. e; Silva, Jean Carl

doi:10.1016/j.jped.2016.04.004

Cited by 37 publications

(46 citation statements)

References 22 publications

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“…However, a study conducted in Fortaleza, Brazil, on which professionals provided information about the disease during prenatal care found that 58.8% of the respondents answered that they had received no information about the disease. Only 17.6% stated that they had received the information from nurses; 17.6% from physician; and 6.0% from pharmacy professionals (6) .…”

Section: Discussionmentioning

confidence: 99%

“…Diabetes mellitus increases the rate of fetal malformations and alters the growth of the unborn child. The incidence of congenital malformations varies from 5.0 to 10.0%, two to three-fold higher than that observed in the general population, and also accounting for about 40.0% of perinatal deaths (6) . Although there is a notable scientific interest in establishing the precise triggering etiologic factors of this clinical condition, few researchers have quantified the risks of major neonatal complications in pregnant women diagnosed with this disease (7) .…”

Section: Introductionmentioning

confidence: 85%

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Instrument for nursing consultation to pregnant women with diabetes mellitus

Filgueiras¹,

Silva²,

Pimenta³

et al. 2019

Rev Rene

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Objective: to construct and validate an instrument to assist the nursing consultation of pregnant women with diabetes mellitus. Methods: methodological study involving the construction of an instrument and evaluation by expert judges in the area who delivered opinions on the objectives, structure, presentation, relevance and content of the instrument of each item. Results: the instrument obtained a satisfactory evaluation in the evaluated criteria, obtaining an index of validity of general content above 85.0% and index of content validity above 80.0% in most of the items. Five items were modified according to the recommendations provided by the judges. Conclusion: the content of the instrument was considered valid to guide the nursing consultation, favoring the promotion of quality of life, adoption of healthy life habits and self-care practices, and provides glimpses of emotional, psychological and social aspects that may influence the endocrine modifications during gestation.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 85%

Instrument for nursing consultation to pregnant women with diabetes mellitus

Filgueiras¹,

Silva²,

Pimenta³

et al. 2019

Rev Rene

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“…Watanabe et al 31 also found a higher rate of cesarean sections among women treated with insulin; in addition, 40% (n ¼ 4) of them were overweight, and 10% (n ¼ 1) had a BMI 30 kg/m 2 before pregnancy, which was not significant. 31,32 Regarding the maternal age and insulin use, no significant differences were found either. Differently, a retrospective study 32 (n ¼ 612 GD cases) showed that the mean age of the women who used insulin was 31.4 years versus 30.9 years for those who did not use it.…”

Section: Discussionmentioning

confidence: 80%

Comparison of Maternal and Fetal Outcomes in Parturients With and Without a Diagnosis of Gestational Diabetes

Freitas

Hintz

Orth

et al. 2019

Rev Bras Ginecol Obstet

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Objective The present study aims to compare the maternal and fetal outcomes of parturients with and without a gestational diabetes diagnosis. Methods A case-control study including parturients with (cases) and without (control) a gestational diabetes diagnosis, who delivered at a teaching hospital in Southern Brazil, between May and August 2018. Primary and secondary data were used. Bivariate analysis and a backward conditional multivariate logistic regression were used to make comparisons between cases and controls, which were expressed by odds ratio (OR), with a 95% confidence interval (95%CI) and a statistical significance level of 5%. Results The cases (n = 47) were more likely to be 35 years old or older compared with the controls (n = 93) (p < 0.001). The cases had 2.56 times greater chance of being overweight (p = 0.014), and a 2.57 times greater chance of having a positive family history of diabetes mellitus (p = 0.01). There was no significant difference regarding weight gain, presence of a previous history of gestational diabetes, height, or delivery route. The mean weight at birth was significantly higher in the infants of mothers diagnosed with diabetes (p = 0.01). There was a 4.7 times greater chance of macrosomia (p < 0.001) and a 5.4 times greater chance of neonatal hypoglycemia (p = 0.01) in the infants of mothers with gestational diabetes. Conclusion Therefore, maternal age, family history of type 2 diabetes, obesity and pregestational overweightness are important associated factors for a higher chance of developing gestational diabetes.

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“…variations were found in the indication of MH in the studies analyzed, where in two of them,Oliveira et al (2019) andSilva et al (2019), there is a percentage greater than 40% in the indication of the drug, while in the other study of the same year byRodrigues et al (2019) we have a decrease in indication, below 30%. It was also observed that in the studies byAmaral et al (2015),Silva et al (2016) andSilveira-Filho et al (2018) the indication of the MH was in a range above 30%.…”

mentioning

confidence: 73%

Use of metformin hydrochloride in gestational diabetes: a systematic review

Torres¹,

Oliveira²,

Nunes³

et al. 2020

RSD

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Gestational Diabetes Mellitus is a condition characterized by an increase in blood glucose levels, which can be initiated or diagnosed during pregnancy. This process occurs due to the production of high levels of hormones by the placenta, most of which are harmful to the action of insulin in the cells increasing the blood sugar level and can affect the growth and well-being of the fetus. Among the drugs used, Metformin Hydrochloride is an oral hypoglycemic drug used to treat Diabetes Mellitus. The present study aimed to elaborate a systematic review on the use of metformin hydrochloride in the treatment of gestational diabetes mellitus. The searches were carried out in the SciElo and Google Acadêmico databases. 763 articles were found in the initial research and after the analysis of the pre-analytical phases, only 6 were selected, since they met the inclusion criteria. After extracting the data, a relationship was made between the use of metformin with the various forms of therapy used in the studies and it was shown that metformin is a drug well applied as monotherapy, being used by 40 % of individuals in one of the studies analyzed and it is also well accepted in combination therapy with insulin in patients who have resistance to it, due to metformin being a drug with easy access and easy dosage. It is concluded that metformin is a safe, effective, low-cost and widely accepted drug for pregnant women who use it in the treatment of gestational Diabetes Mellitus.

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Neonatal outcomes according to different therapies for gestational diabetes mellitus

Abstract: The pediatrician in the delivery room can expect different outcomes for diabetic mothers based on the treatment received.

Cited by 37 publications

References 22 publications

Instrument for nursing consultation to pregnant women with diabetes mellitus

Instrument for nursing consultation to pregnant women with diabetes mellitus

Comparison of Maternal and Fetal Outcomes in Parturients With and Without a Diagnosis of Gestational Diabetes

Use of metformin hydrochloride in gestational diabetes: a systematic review

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