Neonatal pemphigus foliaceus

Hirsch, Ranella J.; Anderson, Judy; Weinberg, Jeffrey M; Burnstein, Penina; Echt, Audrey F; Fermin, Janet; Heilman, Edward; Laude, Teresita A.

doi:10.1067/mjd.2003.339

Cited by 45 publications

(30 citation statements)

References 14 publications

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“…[18,25,26] Only three cases of PF are yet to be reported. [27][28][29] It is postulated to be due to the different distribution of Dsg 1 and 3 in neonate and adult skin and mucosae. [30] Most neonates had skin rather than mucosal lesions.…”

Section: Discussionmentioning

confidence: 97%

Pemphigus and pregnancy: A 23-year experience

Daneshpazhooh¹,

Chams‐Davatchi²,

Valikhani³

et al. 2011

Indian J Dermatol Venereol Leprol

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Section: Discussionmentioning

confidence: 97%

Pemphigus and pregnancy: A 23-year experience

Daneshpazhooh¹,

Chams‐Davatchi²,

Valikhani³

et al. 2011

Indian J Dermatol Venereol Leprol

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“…89 It has been suggested that a higher maternal antibody titer may need to be surpassed before neonatal involvement occurs 90 but too few cases have been reported for conclusions to be drawn.…”

Section: Accepted Manuscriptmentioning

confidence: 98%

“…are special considerations in women of childbearing potential with autoimmune bullous diseases?Transplacental antibody transfer or vertical transmission of pathogenic antibodies has been described in several autoimmune diseases; one well described is neonatal lupus. Pemphigus vulgaris 82 (termed neonatal pemphigus or pemphigus neonatorum), EBA, 83 BP, 84,85 pemphigus vegetans86 and pemphigus foliaceus87,88,89,90 have been reported to be transmitted in this fashion.…”

mentioning

confidence: 97%

Bullous diseases: Kids are not just little people

Marathe

Morel

2015

Clinics in Dermatology

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“…Auch in diesem Fall war die rasche Abheilung sämtlicher Hautveränderungen innerhalb von 2 Tagen unter topischen Kortikosteroiden auffällig. In der serologischen Kontrolluntersuchung nach 2 Wochen war der Pemphigusserumtiter negativ [18].…”

Section: Neonataler Pemphigus Foliaceusunclassified

Pemphiguserkrankungen bei Kindern und Jugendlichen

Meurer

2009

Hautarzt

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The pemphigus diseases, which include some of the most severe bullous autoimmune skin reactions, are seen predominantly in middle-aged and elderly individuals. Only endemic pemphigus foliaceus in South America most frequently affects juveniles and children. All non-endemic pemphigus diseases, including paraneoplastic pemphigus, have been reported to occur in adolescents and even very rarely in children younger than 10 years. Pemphigus vulgaris in pregnancy represents a frequently overseen medical problem and may result in fetal growth retardation, intrauterine death, premature delivery and - in about 30% - in neonatal pemphigus vulgaris of the newborn. Contrary to pemphigus vulgaris, the transplacental crossing of autoantibodies against desmoglein1 in pregnant women with pemphigus foliaceus hardly ever leads to neonatal skin lesions in the offspring. This phenomenon can be explained by differences in the distribution and cross-compensation of the pemphigus antigens desmoglein3 and 1 in neonatal and adult skin or mucosa, respectively.

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Neonatal pemphigus foliaceus

Cited by 45 publications

References 14 publications

Pemphigus and pregnancy: A 23-year experience

Pemphigus and pregnancy: A 23-year experience

Bullous diseases: Kids are not just little people

Pemphiguserkrankungen bei Kindern und Jugendlichen

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