Neonatal Spiradenoma

Tirado-González, Mariantonieta; Beierle, Elizabeth A.; Hammers, Yuki; Andea, Aleodor A.; Mroczek, Elizabeth

doi:10.1111/j.1525-1470.2012.01788.x

Cited by 6 publications

(4 citation statements)

References 4 publications

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“…SA is more common in middle-aged and young patients [6], with no gender difference. SA commonly occurs at head and neck, followed by the trunk and limbs [7].…”

Section: Discussionmentioning

confidence: 91%

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Clinicopathological Characteristics of 11 Cases with Spiradenoma: A Rare Adnexal Tumor

Tian,

Hu,

2024

AJCEM

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Objective: To explore the clinicopathological characteristics of spiradenoma (SA), and make exact diagnosis and differential diagnosis of this disease. Methods: The clinical and pathological data of 11 patients with spiradenoma in the First Affiliated Hospital of Jinan University from 2013 to 2022 were retrospectively analyzed, and combined with the review of literatures. Results: Among the 11 patients with spiroadenomas, 6 cases were male and 5 were female; the age ranged from 19 to 70 years old, with an average age of 41 years; Spiradenomas are more common in the trunk and limbs. At low-power microscope, the tumor mass with capsule in the dermis. Under a high-power microscope, the tumor is usually composed of two types of cells, which are the marginal small basaloid cells with dark staining and central larger cells with a pale and acidophilic nucleus. Other morphological structures included 2 cases of cystic solid and cylindroma respectively. Immunohistochemistry showed that epithelial and myoepithelial differentiation. Conclusion: Spiradenoma often occurs subcutaneously and requires histopathological diagnosis to avoid misdiagnosis. Its biological behavior is benign and its prognosis is good. But malignant transformation should be considered in some case with long course or relapses. SA is rare in clinical and is prone to misdiagnosis or missed diagnosis. This study summarizes the clinilcopathological characteristics of SA, providing reference for future clinical diagnosis and treatment.

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“…SA is more common in middle-aged and young patients [6], with no gender difference. SA commonly occurs at head and neck, followed by the trunk and limbs [7].…”

Section: Discussionmentioning

confidence: 91%

“…SA commonly occurs at head and neck, followed by the trunk and limbs [7]. It can also be seen in rare areas such as the perianal [6], nipple, and auricle [8,9]. These tumors usually present as a single, tender, well circumscribed intradermal nodule [7].…”

Section: Discussionmentioning

confidence: 99%

Clinicopathological Characteristics of 11 Cases with Spiradenoma: A Rare Adnexal Tumor

Tian,

Hu,

2024

AJCEM

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“…Complete excision of the lesions must be carried out to prevent recurrence with a 1 cm safety margin (13). Surgery is generally curative; therefore, additional care is not always necessary.…”

Section: Treatment and Carementioning

confidence: 99%

Eccrine Spiradenoma

Z. TAZI,

E. NGALANDE,

F-Z FDILI

et al. 2024

World J. Adv. Res. Rev.

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First described in 1956, spiradenomas are benign tumors that arise from the bulge of the hair follicle rather than the sweat gland. Epidemiologically, spiradenomas are rare, malignant ones are even rarer, with only around 120 documented cases worldwide. No racial association or sexual predilection for spiradenomas has been reported. Most spiradenomas occur between the ages of 15 and 35. As for malignant spiradenomas, they tend to develop after the age of 50, with a median age of 60 years. Clinically, they are generally skin-colored nodules approximately 1 cm in diameter with a soft consistency, located on the scalp, neck, upper part of the trunk, breasts and rarely the armpits and vulva. While malignant spiradenomas tend to have slightly different characteristics from benign spiradenomas which can metastasize with an estimated rate of 19%. We report the case of a 45-year-old primiparous patient who had been postmenopausal for 5 years and had a maternal aunt who died of breast cancer who consulted for the discovery on self-palpation of a subcutaneous nodule near the left axillary area. The breast examination is unremarkable on D cup breasts with palpation of a subcutaneous nodule measuring 2.5 x 1.5 cm near the left axillary area. Echo mammography finds tissue and cystic lesions of the left breast classified ACR3 and a left axillary subcutaneous lesion measuring 24x13mm that is difficult to characterize. After biopsy of this lesion, the histological and immunohistochemical appearance returned in favor of a cutaneous adnexal tumor compatible with an ECCRINE SPIRADENOMA The extension assessment made by Thoracal abdomino pelvic CT had revealed non-specific pulmonary micronodules to be monitored The patient was sent to multidisciplinary team discussion with the decision to perform a left lumpectomy of the axillary lesion. The management of malignant spiradenomas is multidisciplinary with a surgeon, an oncologist and possibly a radiation oncologist.

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“…Eccrine Spiradenoma Arising in A Old Scar Tissue Annals of Pathology and Laboratory Medicine, Vol. 10, Issue 0, Aug 2023 old baby has been documented in literature [4].…”

Section: C-36mentioning

confidence: 99%