Neonatal stretched penile length: relationship with gestational maturity and anthropometric parameters at birth

Abstract

SPL should be interpreted in relation to anthropometric parameters in newborns, particularly body and foot length.

Assessment of the stretched penile length in Sri Lankan newborns

“…Sertoli cells begin to secrete Anti Mullerian Hormone around the 7 th week of gestation and Leydig cells start secreting Testosterone around 11th to 12 th weeks of gestation [1]. Placental Human Chorionic Gonadotrophin-testes axis stimulates Leydig cells from 8 th to 14 th weeks, while foetal Hypothalamic-Pituitary-Gonadal axis activation occurs around 15th week of gestation [1,2]. The onset of foetal penile growth which is dependent on the foetal androgen exposure, occurs at 8 th to 14 th weeks of gestation and a rapid growth is observed at 7mm/week from 14 weeks to term [1,2].…”

“…Placental Human Chorionic Gonadotrophin-testes axis stimulates Leydig cells from 8 th to 14 th weeks, while foetal Hypothalamic-Pituitary-Gonadal axis activation occurs around 15th week of gestation [1,2]. The onset of foetal penile growth which is dependent on the foetal androgen exposure, occurs at 8 th to 14 th weeks of gestation and a rapid growth is observed at 7mm/week from 14 weeks to term [1,2]. Following this growth period, another period of rapid growth occurs at mini-puberty, during the first 3 months of life [2,3].…”

“…The onset of foetal penile growth which is dependent on the foetal androgen exposure, occurs at 8 th to 14 th weeks of gestation and a rapid growth is observed at 7mm/week from 14 weeks to term [1,2]. Following this growth period, another period of rapid growth occurs at mini-puberty, during the first 3 months of life [2,3]. In the foetus, growth of the penis is due to the action of testosterone and dihydrotestosterone during the second and third trimester, which is regulated by Luteinizing hormone [4].…”

“…Micropenis with undescended testes is a feature of underlying congenital hypopituitarism, which is associated with hypogonadotropic hypogonadism [2,5]. It is also seen in syndromes such as Klinefelter, Prader Willi, Noonan [2,5].…”

“…Micropenis with undescended testes is a feature of underlying congenital hypopituitarism, which is associated with hypogonadotropic hypogonadism [2,5]. It is also seen in syndromes such as Klinefelter, Prader Willi, Noonan [2,5]. Ambiguous genitalia in an under virialized male with hypospadias and undescended testes may be the initial presentation of a rare form of congenital adrenal hyperplasia [5].…”