Nervous system involvement in association with vasculitis and anticardiolipin antibodies in a patient with systemic sclerosis.

Systemic sclerosis and multiple sclerosis

“…Few cases of CNS involvement have been reported in SSc, including encephalitis [11], subarachnoid [18] or cerebral [6] hemorrhage, cerebral infarction [1,17], transient ischemic attacks [13], and seizures [5,8,13,14]. Many of these events cannot be considered the result of primary CNS involvement [13] but rather are secondary to renal or cardiopulmonary involvement [10].…”

“…Many of these events cannot be considered the result of primary CNS involvement [13] but rather are secondary to renal or cardiopulmonary involvement [10]. Nevertheless, vasculitic damage has been detected in only three cases [8,17,18].…”