Network analysis of RE-AIM framework: chronology of the field and the connectivity of its contributors

Shoup, Jo Ann; Gaglio, Bridget; Varda, Danielle M.; Glasgow, Russell E.

doi:10.1007/s13142-014-0300-1

Cited by 14 publications

(10 citation statements)

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“…The EPIS framework is a relatively young model compared to some other implementation models and frameworks in the field. It is natural that after initial introduction and application, the network of users will broaden [26]. This has already been observed with EPIS, as more than 50% of research projects included in this review had no direct affiliation with the first author of the EPIS framework (Aarons).…”

Section: Discussionmentioning

confidence: 85%

Systematic review of the Exploration, Preparation, Implementation, Sustainment (EPIS) framework

et al. 2019

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BackgroundEffective implementation of evidence-based practices (EBPs) remains a significant challenge. Numerous existing models and frameworks identify key factors and processes to facilitate implementation. However, there is a need to better understand how individual models and frameworks are applied in research projects, how they can support the implementation process, and how they might advance implementation science. This systematic review examines and describes the research application of a widely used implementation framework, the Exploration, Preparation, Implementation, Sustainment (EPIS) framework.MethodsA systematic literature review was performed to identify and evaluate the use of the EPIS framework in implementation efforts. Citation searches in PubMed, Scopus, PsycINFO, ERIC, Web of Science, Social Sciences Index, and Google Scholar databases were undertaken. Data extraction included the objective, language, country, setting, sector, EBP, study design, methodology, level(s) of data collection, unit(s) of analysis, use of EPIS (i.e., purpose), implementation factors and processes, EPIS stages, implementation strategy, implementation outcomes, and overall depth of EPIS use (rated on a 1–5 scale).ResultsIn total, 762 full-text articles were screened by four reviewers, resulting in inclusion of 67 articles, representing 49 unique research projects. All included projects were conducted in public sector settings. The majority of projects (73%) investigated the implementation of a specific EBP. The majority of projects (90%) examined inner context factors, 57% examined outer context factors, 37% examined innovation factors, and 31% bridging factors (i.e., factors that cross or link the outer system and inner organizational context). On average, projects measured EPIS factors across two of the EPIS phases (M = 2.02), with the most frequent phase being Implementation (73%). On average, the overall depth of EPIS inclusion was moderate (2.8 out of 5).ConclusionThis systematic review enumerated multiple settings and ways the EPIS framework has been applied in implementation research projects, and summarized promising characteristics and strengths of the framework, illustrated with examples. Recommendations for future use include more precise operationalization of factors, increased depth and breadth of application, development of aligned measures, and broadening of user networks. Additional resources supporting the operationalization of EPIS are available.Electronic supplementary materialThe online version of this article (10.1186/s13012-018-0842-6) contains supplementary material, which is available to authorized users.

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Section: Discussionmentioning

confidence: 85%

Systematic review of the Exploration, Preparation, Implementation, Sustainment (EPIS) framework

et al. 2019

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“…Key considerations to begin implementing mHealth for hydroxyurea utilization include recruitment in diverse care settings and estimating the reach, effectiveness, adoption, implementation, and maintenance of the apps, which are the 5 components of the RE-AIM framework [ 61 ]. RE-AIM is a useful framework to evaluate the utility of mHealth to foster hydroxyurea utilization and to broaden the future applicability and dissemination of the apps [ 62 , 63 ].…”

Section: Methodsmentioning

confidence: 99%

Integration of Mobile Health Into Sickle Cell Disease Care to Increase Hydroxyurea Utilization: Protocol for an Efficacy and Implementation Study

et al. 2020

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Background Hydroxyurea prevents disease complications among patients with sickle cell disease (SCD). Although its efficacy has been endorsed by the National Health Lung and Blood Institute evidence-based guidelines, its adoption is low, both by patients with SCD and providers. Mobile health (mHealth) apps provide benefits in improving medication adherence and self-efficacy among patients with chronic diseases and have facilitated prescription among medical providers. However, mHealth has not been systematically tested as a tool to increase hydroxyurea adherence nor has the combination of mHealth been assessed at both patient and provider levels to increase hydroxyurea utilization. Objective This study aims to increase hydroxyurea utilization through a combined two-level mHealth intervention for both patients with SCD and their providers with the goals of increasing adherence to hydroxyurea among patients and improve hydroxyurea prescribing behavior among providers. Methods We will test the efficacy of 2 mHealth interventions to increase both patient and provider utilization and knowledge of hydroxyurea in 8 clinical sites of the NHLBI-funded Sickle Cell Disease Implementation Consortium (SCDIC). The patient mHealth intervention, InCharge Health, includes multiple components that address memory, motivation, and knowledge barriers to hydroxyurea use. The provider mHealth intervention, Hydroxyurea Toolbox (HU Toolbox), addresses the clinical knowledge barriers in prescribing and monitoring hydroxyurea. The primary hypothesis is that among adolescents and adults with SCD, adherence to hydroxyurea, as measured by the proportion of days covered (the ratio of the number of days the patient is covered by the medication to the number of days in the treatment period), will increase by at least 20% after 24 weeks of receiving the InCharge Health app, compared with their adherence at baseline. As secondary objectives, we will (1) examine the change in health-related quality of life, acute disease complications, perceived health literacy, and perceived self-efficacy in taking hydroxyurea among patients who use InCharge Health and (2) examine potential increases in the awareness of hydroxyurea benefits and risks, appropriate prescribing, and perceived self-efficacy to correctly administer hydroxyurea therapy among SCD providers between baseline and 9 months of using the HU Toolbox app. We will measure the reach, adoption, implementation, and maintenance of both the InCharge Health and the HU Toolbox apps using the reach, effectiveness, adoption, implementation, and maintenance framework and qualitatively evaluate the implementation of both mHealth interventions. Results The study is currently enrolling study participants. Recruitment is anticipated to be completed by mid-2021. Conclusions If this two-level intervention, that is, the combined use of InCharge Health and HU Toolbox apps, demonstrates efficacy in increasing adherence to hydroxyurea and prescribing behavior in patients with SCD and their providers, respectively, both apps will be offered to other institutions outside the SCDIC through a future large-scale implementation-effectiveness study. Trial Registration ClinicalTrials.gov NCT04080167; https://clinicaltrials.gov/ct2/show/NCT04080167 International Registered Report Identifier (IRRID) DERR1-10.2196/16319

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“…The seminal RE-AIM paper (1) has been cited over 2,800 times, and the RE-AIM framework has been applied to study planning or evaluation in over 450 publications (7). RE-AIM is one of the most frequently used frameworks for planning and evaluation of grant applications at most of the leading U.S. health and medical research agencies (8) and has been used widely (nationally and internationally) (9, 10) and across populations, settings, and health conditions (11–24). Generally, RE-AIM does seem to translate and be useful in the different countries and cultures in which use has been reported.…”

Section: Introductionmentioning

confidence: 99%

RE-AIM Planning and Evaluation Framework: Adapting to New Science and Practice With a 20-Year Review

Glasgow

Harden

Gaglio

et al. 2019

Front. Public Health

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The RE-AIM planning and evaluation framework was conceptualized two decades ago. As one of the most frequently applied implementation frameworks, RE-AIM has now been cited in over 2,800 publications. This paper describes the application and evolution of RE-AIM as well as lessons learned from its use. RE-AIM has been applied most often in public health and health behavior change research, but increasingly in more diverse content areas and within clinical, community, and corporate settings. We discuss challenges of using RE-AIM while encouraging a more pragmatic use of key dimensions rather than comprehensive applications of all elements. Current foci of RE-AIM include increasing the emphasis on cost and adaptations to programs and expanding the use of qualitative methods to understand “how” and “why” results came about. The framework will continue to evolve to focus on contextual and explanatory factors related to RE-AIM outcomes, package RE-AIM for use by non-researchers, and integrate RE-AIM with other pragmatic and reporting frameworks.

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Network analysis of RE-AIM framework: chronology of the field and the connectivity of its contributors

Cited by 14 publications

References 55 publications

Systematic review of the Exploration, Preparation, Implementation, Sustainment (EPIS) framework

Systematic review of the Exploration, Preparation, Implementation, Sustainment (EPIS) framework

Integration of Mobile Health Into Sickle Cell Disease Care to Increase Hydroxyurea Utilization: Protocol for an Efficacy and Implementation Study

RE-AIM Planning and Evaluation Framework: Adapting to New Science and Practice With a 20-Year Review

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