Neural Systems Underlying the Recognition of Familiar and Newly Learned Faces

Leveroni, Catherine L.; Seidenberg, Michael; Mayer, Andrew R.; Mead, Larissa A.; Binder, Jeffrey R.; Rao, Stephen M.

doi:10.1523/jneurosci.20-02-00878.2000

Cited by 437 publications

(319 citation statements)

References 49 publications

Supporting

Mentioning

276

Contrasting

Unclassified

Order By: Relevance

“…As in the previous study (5,16), no major hemispheric predominance seemed to be effective for the EP components. That a multitude of brain regions participated in face processing was supported by a recent fMRI study (14).…”

Section: Category-related Processing: Faces Versus Nonface Stimulimentioning

confidence: 83%

“…However, while these studies demonstrated relevant time epochs, the localization of these processes needs to be done using complementary techniques. Thus, over the last 10 to 20 years, positron emission tomography (PET) and functional MRI studies looked further into the anatomical correlates in vivo (12)(13)(14). While the underlying brain structures can now be precisely localized to within a precision of a few millimeters, no information about the temporal aspects of face processing was obtained using these techniques.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Intracranial Neurophysiological Correlates Related to the Processing of Faces

Seeck¹,

Michel²,

Blanke³

et al. 2001

Epilepsy & Behavior

View full text Add to dashboard Cite

Face perception and recognition is an intriguing ability, already present in neonates. Numerous studies in patients with brain lesions identified the temporo-occipital cortex as the crucial structure for this capacity. Analysis of electrical signals (EEG) inside the brain of patients implanted with intracranial electrodes for diagnostic purposes allows researchers to describe the temporal and spatial organization of responses to various aspects of face processing in human subjects. Several findings have emerged and appear relevant for cerebral organization in general: (1) Selective face responses were obtained from the basal temporo-occipital cortex at around 200 ms (N200); however, other structures such as the lateral temporal lobe and frontal cortex also participate in face recognition and perception tasks. (2) Each structure has a distinct "response profile"; that is, with respect to a given task certain structures respond strongly, others less or not at all. This profile might change with a different task, although the physical parameters of the stimuli remain the same. (3) The right hemispheric predominance of face processing, as suggested by patient data and studies in healthy volunteers, seemed to be restricted to its early stages (i.e., before 100 -150 ms). (4) Recognition of faces might be associated with differential intracranial responses, despite an incorrect overt response, reflecting neurophysiological correlates of implicit memory. (5) The more the stimulus resembled a complete human face, the earlier and larger the N200 response was found, in particular over the basal temporobasal cortex. Analysis of electrical signals from intracranial electrodes might help to improve our understanding of the underlying physiological and anatomical constraints of cognitive processes.

show abstract

Section: Category-related Processing: Faces Versus Nonface Stimulimentioning

confidence: 83%

mentioning

confidence: 99%

Intracranial Neurophysiological Correlates Related to the Processing of Faces

Seeck¹,

Michel²,

Blanke³

et al. 2001

Epilepsy & Behavior

View full text Add to dashboard Cite

show abstract

“…The sources for the components with latencies of about 400 ms in face/word tasks have been located by other authors to be in the temporal and frontal cortices (Halgren et al, 1994a,b). Wide, mostly temporal, networks are implicated in the metabolic studies as sources for personal identity-related brain activity (Haxby et al, 2000;Leveroni et al, 2000;Tempini et al, 1998). It is possible that our temporal sources (dipoles 3 and 4) reflect such activity, at least partially.…”

Section: Discussionmentioning

confidence: 99%

Familiar-face recognition and comparison: source analysis of scalp-recorded event-related potentials

Mnatsakanian

Tarkka

2004

Clinical Neurophysiology

View full text Add to dashboard Cite

Objective: We studied the event-related potentials elicited by categorical matching of faces. The purpose was to find cortical sources responsible for face recognition and comparison.Methods: Nineteen healthy volunteers participated in the study. Each trial began with one of the two cues (S1) followed by consecutive pictures (S2 and S3). Each picture was a photograph of a familiar face with a superimposed abstract dot pattern. One cue directed attention to compare faces and another to compare patterns. 128-channel electroencephalogram was recorded. Spatio-temporal multiple dipole source models were generated using Brain Electromagnetic Source Analysis 2000, for the window of 80 -600 ms from S3 onset.Results: The obtained model for face recognition and comparison contained 8 dipoles explaining 97% of grand average and about 90% of individual data and showing temporal and spatial separation of sources: in the frontal region, in the occipital cortex, and in the bilateral medial temporal and inferotemporal regions. Different faces elicited larger components than same person's faces around 400 ms, mainly explained by frontal dipoles.Conclusions: The sources in our models estimate the activity common for both Face task conditions (the recognition of a familiar person) and also differential activity, related to the match/mismatch item processing.

show abstract

“…Furthermore, the PCC activation is also elicited during recognition of visual and auditory materials drawn from a person's daily life. When individuals are presented with names of friends and family (Maddock, Garrett, & Buonocore, 2001), faces and voices of friends and family (Shah et al, 2001), famous faces (Leveroni et al, 2000), personal belongings (Leveroni et al, 2000;Sugiura, Shah, Zilles, & Fink, 2005), familiar places (Sugiura et al, 2005), and personal life events (Addis, Moscovitch, Crawley, & McAndrews, 2004;Levine et al, 2004), PCC activation is more pronounced than when viewing similarly constructed, but novel materials.…”

Section: Introductionmentioning

confidence: 99%

Task-dependent posterior cingulate activation in mild cognitive impairment

et al. 2006

View full text Add to dashboard Cite

Neuroimaging research has demonstrated that the posterior cingulate cortex (PCC) is functionally compromised in individuals diagnosed with amnestic Mild Cognitive Impairment (MCI), a major risk factor for the development of Alzheimer's disease (AD). In functional magnetic resonance imaging (fMRI) studies with healthy participants, this same region is active during self-appraisal (requiring retrieval of semantic knowledge about the self) as well as episodic recognition of recentlylearned information. Administering both types of tasks to people with MCI may reveal important information regarding the role of the PCC in recollection. This study investigated fMRI activation in the PCC in individuals with MCI and age, gender, and education-matched controls across two tasks. The first task was a visual episodic recognition task in which participants indicated whether pictures had or had not been presented during a study session. The second task was an autobiographical self-appraisal task in which subjects rated themselves on a set of trait adjectives. Results of a conjunction analysis revealed the PCC as the sole region commonly active during both tasks in the healthy older adults. Furthermore, additional analysis revealed an interaction in the PCC indicating a task-dependent response in the MCI group. MCI participants showed PCC activation during self-appraisal, but not during episodic retrieval. These results suggest in MCI that the PCC shows functional degradation during episodic retrieval of visual information learned in the laboratory. In contrast, the PCC's role in retrieval and evaluation of highly-elaborated information regarding the self is more well-preserved.

show abstract

Neural Systems Underlying the Recognition of Familiar and Newly Learned Faces

Cited by 437 publications

References 49 publications

Intracranial Neurophysiological Correlates Related to the Processing of Faces

Intracranial Neurophysiological Correlates Related to the Processing of Faces

Familiar-face recognition and comparison: source analysis of scalp-recorded event-related potentials

Task-dependent posterior cingulate activation in mild cognitive impairment

Contact Info

Product

Resources

About