“…Previously, we discussed an individual patient data meta-analysis where higher mean SBPs post-EVT were associated with unfavorable outcomes. 16,17 ENCHANTED2/MT ([Second Enhanced Control of Hypertension and Thrombectomy Stroke Study] a multicenter open-label blinded RCT) is now completed with 821 patients randomized to more (<120 mm Hg) versus less intensive (140–180 mm Hg) SBP control for 72 hours. 5 Again, odds of worse primary outcome (ordinal mRS analysis) were greater with intensive treatment (OR, 1.37 [95% CI, 1.07–1.76]).…”