2020
DOI: 10.1097/qai.0000000000002389
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Neurocytoskeleton Proteins in Cerebrospinal Fluid of People With HIV-1 Subtypes B and C

Abstract: Background:The objective was to compare the effect of HIV-1C and HIV-1B subtypes on neurofilament light (NfL) cerebrospinal fluid (CSF) levels and ratios of NfL to tau proteins. Additional comparisons were performed between people with HIV (PWH), participants with Alzheimer disease (AD), and HIV-negative controls (HIV-). We also calculated the diagnostic characteristics of CSF NfL and its ratios in HIV-associated neurocognitive disorder (HAND) diagnosis.Methods: CSF NfL, T-tau, and P-tau 181 concentrations wer… Show more

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Cited by 2 publications
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