Neuroendocrine hypothalamus as a homeostat of endogenous time

Chernysheva, M. P.; Nozdrachev, A. D.

doi:10.1134/s002209301701001x

Cited by 4 publications

(2 citation statements)

References 60 publications

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“…The hypothalamus is a small area in the diencephalon that includes a large number of cell groups (more than 30 nuclei) that regulate the neuroendocrine activity of the brain and homeostasis of the body [1][2][3][4]. The hypothalamus is connected by nerve pathways with almost all parts of the central nervous system, including the cortex, hippocampus, amygdala, cerebellum, brain stem, and spinal cord [5].…”

Section: Introductionmentioning

confidence: 99%

“…Recent studies show that the hypothalamus plays an important role in higher functions, such as memory and emotional state, and thus participates in the formation of various aspects of behavior [2,7,8]. The hypothalamus controls the activity of the human endocrine system, due to the fact that its neurons are able to secrete neuroendocrine transmitters (liberins and statins) that stimulate or inhibit the production of hormones from the adenohypophysis [3,5]. Suppression of the functional activity of the hypothalamus leads to a violation of drinking and eating behavior [9].…”

Section: Introductionmentioning

confidence: 99%

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Participation of Various Nuclei of the Hypothalamus in the Implementation of the Drinking Skill Developed

Baghirova¹

2021

BJSTR

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In order to study the role of various nuclei of the hypothalamus in the implementation of the drinking skill developed electrostimulation and temporary shutdown were performed supraoptic (SO), ventromedial (VMH) and medial-mamillary (MM) nuclei of the hypothalamus. The registration of the amount of consumed water showed the following: electrostimulation of SO, unlike VMH and MM of hypothalamic nuclei caused additional water consumption in comparison with the background. The application of novocaine in SO led to a significant decrease in the amount of water consumed, which decreased for the duration of the action of novocaine (40-50 minutes) and amounted to 60-70 ml instead of 120 in the norm. Bilateral novocaine blockade of SO led to a complete inhibition of the performance of the developed drinking skill. Thus, the results of the studies carried out on electrical stimulation and temporary switching off of the SO suggest that the osmoreceptors of the SO of the anterior hypothalamus play a certain role in the processes of the formation of thirst.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Participation of Various Nuclei of the Hypothalamus in the Implementation of the Drinking Skill Developed

Baghirova¹

2021

BJSTR

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Homeostasis and adaptation: pathophysiological aspects of somato-vegetative interaction in ontogenesis

Артеменков

2021

Pediatr (SPb)

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The review presents information on the somatovegetative interaction of blood circulation and respiration from the point of view of the views of Professor Yu.P. Pushkarev. Data are presented that speak of the complexity and complexity of the problem of homeostasis and adaptation, the unresolved many issues that are important for understanding the stability of the internal environment of the body and establishing the limits of the norm. It has been shown that within the neurohumoral system of the body, the interaction of various components of functional systems is constantly carried out, ensuring the conjugation of respiration and blood circulation with the formation of intersystem links. Some aspects of the formation of functions in animals and humans in postnatal ontogenesis are considered. It is emphasized that homeostasis is an internal balance of indicators in the body, but its values are constantly changing due to the center-peripheral integration of functions. It was emphasized that the process of achieving a beneficial adaptive result is characterized by the asymmetry of physiological indicators, and the intersystem interaction ensures the balancing of homeostasis constants in terms of adaptation to environmental conditions. It has been shown that over-threshold environmental influences and homeostasis parameters shift in the body, compensatory-adaptive reactions occur, aimed at maintaining a certain level of stationary state, eliminating or limiting the effect of the harmful factor and optimizing the interaction of the organism and the environment due to the formation of intersystem links. Analyzed the pathophysiological mechanisms of changes in function in certain diseases and stress effects. It is shown that the further study of the somatovegetative interaction in the context of the ideas of Yu.P. Pushkarev will allow revealing the true mechanisms of synchronization of functions in the organism of animals and humans in order to understand its existence as an independent self-regulating system.

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Hypothalamic Syndrome. The Role of the Hypothalamus in the Formation of Eating Behavior and Obesity

Nikonova¹,

Tishkovskiy²,

Butrim³

et al. 2019

Journal GrSMU

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Причины избыточной массы тела и ожирения многообразны. В их основе лежит нарушение энергетического баланса, гиподинамия, а также нарушение нейроэндокринных механизмов, которые играют важную роль в формировании пищевого поведения человека. В настоящем обзоре проанализированы литературные сведения о взаимосвязи гипофиза, гипоталамуса, гормонов и нейромедиаторов в формировании пищевого поведения и ожирения.

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Neuroendocrine hypothalamus as a homeostat of endogenous time

Cited by 4 publications

References 60 publications

Participation of Various Nuclei of the Hypothalamus in the Implementation of the Drinking Skill Developed

Participation of Various Nuclei of the Hypothalamus in the Implementation of the Drinking Skill Developed

Homeostasis and adaptation: pathophysiological aspects of somato-vegetative interaction in ontogenesis

Hypothalamic Syndrome. The Role of the Hypothalamus in the Formation of Eating Behavior and Obesity

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