Neurologic sequelae after caesarean section

Rorarius, M. G. F.; Suominen, P.; Haanpää, Maija; Puura, A.; Baer, G.; Pajunen, P.; Tuimala, Risto

doi:10.1034/j.1399-6576.2001.450106.x

Cited by 28 publications

(13 citation statements)

References 43 publications

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“…Transient neurologic symptoms (TNS) are the most common clinical symptoms, marked by pain in the lower limbs, hyposthesia or allergy. Occasionally, this is accompanied by weakness in the lower limbs or urinary retention (14,15). Numerous studies have been conducted in regard to peripheral neurotoxicity.…”

Section: Discussionmentioning

confidence: 99%

Cytotoxicity study on SH-SY5Y cells cultured at high glucose levels and treated with bupivacaine

Zhang

et al. 2013

Molecular Medicine Reports

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The aim of this study was to investigate susceptibility to the neurotoxicity of local anesthetic agents in a model of gestational diabetes mellitus (GDM). SH-SY5Y cells were cultured at different concentrations of glucose and subsequently treated with 1 mmol/l bupivacaine for 6 h. Reactive oxygen species (ROS) production and apoptosis were assessed using flow cytometry in each group of cells. The MTT method was utilized to detect cell survival, and western blot analysis was used to examine changes in 78 kDa glucose‑regulated protein (GRP78) levels in neuronal cells. In all groups, levels of ROS production, cell survival and GRP78 expression were significantly different (P<0.01) following the addition of various concentrations of glucose and bupivacaine, as well as for the interaction between different concentrations of the anesthetic agents, demonstrating a statistically significant difference. In conclusion, the susceptibility of SH-SY5Y cells to the neurotoxicity of local anesthetic agents was enhanced in a model of GDM.

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Section: Discussionmentioning

confidence: 99%

Cytotoxicity study on SH-SY5Y cells cultured at high glucose levels and treated with bupivacaine

Zhang

et al. 2013

Molecular Medicine Reports

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“…Thirty-nine studies (16 RCT, [10][11][12]14,[16][17][18][19][20][21]23,24,26,[28][29][30] ten cohort studies, [33][34][35][36][38][39][40][41][42][43] and 13 case series 45,[47][48][49][50][51][53][54][55][56][57][58][59][60] ) contained data on frequency of ADP or PDPH (Table I). Figures 1 to 3 summarize the meta-analyses of ADP and PDPH risks for different epidural and spinal needles.…”

Section: Dp and Pdph Ratesmentioning

confidence: 99%

PDPH is a common complication of neuraxial blockade in parturients: a meta-analysis of obstetrical studies

Choi

Galinski

Takeuchi

et al. 2003

Can J Anesth/J Can Anesth

334

182

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P Pu ur rp po os se e: : Postdural puncture headache (PDPH) is an iatrogenic complication of neuraxial blockade. We systematically reviewed the literature on parturients to determine the frequency, onset, and duration of PDPH. M Me et th ho od ds s: :Citations on PDPH in the obstetrical population were identified by computerized searches, citation review, and hand searches of abstracts and conference proceedings. Citations were included if they contained extractable data on frequency, onset, or duration of PDPH. Using meta-analysis, we calculated pooled estimates of the frequency of accidental dural puncture for epidural needles and pooled estimates of the frequencies of PDPH for epidural and spinal needles.R Re es su ul lt ts s: : Parturients have approximately a 1.5% [95% confidence interval (CI) 1.5% to 1.5%) risk of accidental dural puncture with epidural insertion. Of these, approximately half (52.1%; 95% CI, 51.4% to 52.8%) will result in PDPH. The risk of PDPH from spinal needles diminishes with small diameter, atraumatic needles, but is still appreciable (Whitacre 27-gauge needle 1.7%; 95% CI, 1.6% to 1.8%). PDPH occurs as early as one day and as late as seven days after dural puncture and lasts 12 hr to seven days. C Co on nc cl lu us si io on n: : PDPH is a common complication for parturients undergoing neuraxial blockade. Objectif : Les céphalées post-ponction durale (CPPD) sont une complication iatrogène du bloc neuraxial. Une revue systématique des publications sur les parturientes a permis de déterminer la fréquence, le délai d'installation et la durée des CPPD. Méthode : Les citations sur les CPPD dans la population obstétricale ont été repérées par des recherches informatisées, la revue des références et des recherches manuelles de résumés et de comptes rendus de conférences. Les références retenues devaient comporter des données sur la fréquence, le délai d'installation et la durée des

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“…Transient neurologic symptoms have been reported after spinal administration of mepivacaine [18] and bupivacaine [19]. However, none of our parturients had complains about transient neurologic symptoms.…”

Section: Discussionmentioning

confidence: 55%

Mepivacaine for Spinal Anesthesia in Parturients Undergoing Elective Cesarean Delivery: Maternal and Neonatal Plasma Concentrations and Neonatal Outcome

Bremerich

Schlößer²,

LʼAllemand³

et al. 2003

Zentralbl Gynakol

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Neurologic sequelae after caesarean section

Cited by 28 publications

References 43 publications

Cytotoxicity study on SH-SY5Y cells cultured at high glucose levels and treated with bupivacaine

Cytotoxicity study on SH-SY5Y cells cultured at high glucose levels and treated with bupivacaine

PDPH is a common complication of neuraxial blockade in parturients: a meta-analysis of obstetrical studies

Mepivacaine for Spinal Anesthesia in Parturients Undergoing Elective Cesarean Delivery: Maternal and Neonatal Plasma Concentrations and Neonatal Outcome

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