Neuron-specific enolase (NSE) in small-cell lung cancer: longitudinal tumor marker evaluation

Cyfra 21-1 as a Biologic Marker of Non-small Cell Lung Cancer

“…3 In small cell lung cancer (SCLC), median survival is 10 to 18 months in the limited disease stage and 7 to 12 months in extensive disease. 9 Unfortunately, NSE lacks specificity and like CEA, occasionally is elevated in nonmalignant conditions. 5 · 6 Tumor markers, including carcinoembryonic antigen (CEA), neuron-specific enolase (NSE), and squamous cell carcinoma (SCC) antigen have been investigated for putative diagnostic and prognostic value.…”