Nevus Lipomatosus Cutaneous Superficialis

Giant Nevus Lipomatosus Cutaneus Superficials: Case Report and Review of the Literature

“…Inflammatory cells (lymphocytes, histiocytes and mast cells) can be observed around vessels of the dermis and subcutis. Lipoblasts are not found, and the blood vessels are normal (10).…”

“…Several theories have been proposed to explain the pathogenesis of NLCS. The currently accepted one is that NLCS develops from messenchymal perivascular cells present first as primitive lipoblasts that subsequently transform into mature lipocytes (5,8,(10)(11)(12). There is no evidence that the deposition of adipose tissue is secondary to degenerative changes in dermal collagen or elastic tissue as Zurhelle and Hoffman originally stated (13), and Nikolowsky also noted and agreed (14).…”

Nevus lipomatosus cutaneus superficialis with follicular papules and hypertrophic pilo-sebaceous units

“…The classical appearance of the multiple type has been described as smooth or wrinkled, skin‐colored plaques or yellowish nodules around the pelvic girdle areas, which often show zonal or zosteriform distribution 2–4 . However, there is a broad variety in the number of the nodules, as well as in the clinical features, which include cerebriform shapes 5 , peau d’orange surface, comedo‐like plugs 3 , verrucous papules 6 , hairiness 2 and association with hemangiomas 7 . Our case is clinically unusual, because she showed a flabby and bulky tumor in the lateral chest with coalesced follicular papules and hypertrichosis on the surface.…”

Giant Nevus Lipomatosus Superficialis Associated with Cavernous Hemangioma

“…Their surfaces are usually smooth, but they may be wrinkled, verrucoid, or have a peau d'orange appearance. In addition, there may be dilata- tion of the infundibulum of the hair follicle, with plugging and comedon formation (3). The lesions vary in size, generally appear at the same time, and, once formed, usually remain unchanged, although some continue to enlarge for years (4).…”

“…The lesions vary in size, generally appear at the same time, and, once formed, usually remain unchanged, although some continue to enlarge for years (4). The nodules are generally asymptomatic and treatment is usually unnecessary (3).…”