Nevus lipomatosus cutaneous superficialis

Abstract

Nevus lipomatosus cutaneous superficialis is a rare benign hamartomatous skin tumor characterized by dermal deposition of mature adipose tissue. Two clinical forms have been described (classical and solitary types). We describe a case of nevus lipomatosus cutaneous superficialis with a 13-year history of growth in a young woman who had a solitary skin-colored tumoral mass on the right buttock. Histopathological findings were typical and confirmed the diagnosis. In this case, the lesion was a skin-colored isolated mass, as described in the solitary type, but its localization and age of appearance were compatible with the classical type. The combination of simultaneous clinical findings of both types had not been published before.

Nevus lipomatosus cutaneous superficialis on the shoulder: A case report with MRI findings

“…With regard to clinical form, it is classified as either the multiple (or “classical”) form or solitary form. The multiple form frequently occurs in the lower back and buttocks of young patients, from birth to 20 years of age, and it is characterized by clusters of skin-colored or yellow papules or nodules [2]. There is no observed sexual or familial trend [3].…”

“…The adipocytes commonly form small aggregates around blood vessels or eccrine glands but may also manifest as solitary adipocytes between collagen bundles. The epidermis exhibits acanthosis, basket weave hyperkeratosis, and increased basal pigmentation [2]. NLCS can increase in size.…”

Genital nevus lipomatosus cutaneous superficialis: A diagnostic challenge in a pediatric patient

“…A definitive diagnosis can be made with biopsy. Histopathologic examination classically demonstrates a proliferation of ectopic mature adipocytes in the reticular dermis, comprising up to 50% of the lesion . NLCS is a benign condition that does not require treatment .…”

“…Histopathologic examination classically demonstrates a proliferation of ectopic mature adipocytes in the reticular dermis, comprising up to 50% of the lesion. 11 NLCS is a benign condition that does not require treatment. 2 If desired, definitive treatment for NLCS is surgical excision and recurrence thereafter is rare.…”

Multiple yellow nodules in a 13-year-old girl

“…Clinically important differential diagnoses of NLCS include naevus sebaceous, plexiform neurofibroma, focal dermal hypoplasia, segmental neuroma, connective tissue naevus, angiolipoma and lipomatosis . Histologically, other types of connective tissue naevus, focal dermal hypoplasia, intradermal melanocytic naevus, and pedunculated lipofibroma should be excluded, as some of these are associated with malignancies.…”