New advances into antimicrobial research

Liu, Xin; Li, Yanhua; Guo, Jinshan

doi:10.1111/1751-7915.13910

Cited by 3 publications

(4 citation statements)

References 11 publications

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“…These microorganisms are prone to forming biofilms and developing drug resistance under harsh environmental conditions, posing a serious threat to human health. According to the World Health Organization, drug-resistant diseases contribute to a global mortality rate of approximately 700,000 individuals ( Liu et al, 2022 ). Further studies are required to identify agents that can reduce biofilm formation and decrease drug resistance.…”

Section: Discussionmentioning

confidence: 99%

The combination of allicin with domiphen is effective against microbial biofilm formation

Li,

Wang,

et al. 2024

Front. Microbiol.

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BackgroundMicroorganisms in biofilms are particularly difficult to control because of their increased survival and antibiotic resistance. Allicin and domiphen were employed to inhibit the microbial growth and biofilm formation of Staphylococcus aureus, Escherichia coli, and Candida albicans strains.MethodsBroth microdilution method and checkerboard assay were conducted to determine the efficacy of allicin combined with domiphen against S. aureus, E. coli, and C. albicans. Microbial biofilm formation was measured using the crystal violet staining method and fluorescence microscopy. And the total viable count of the biofilm cells on material surface after the treatment with antimicrobial reagents was calculated with the plate count technique.ResultsThe two drugs showed synergistic effects against the pathogens with a fractional bactericidal concentration of less than 0.38. The combination of 64 μg/mL allicin with 1 μg/mL domiphen dispersed over 50% of the biofilm mass of S. aureus, E. coli, and C. albicans. In addition, the drug combination reduced the total viable counts of E. coli and C. albicans biofilm cells on stainless steel and polyethylene surfaces by more than 102 CFU/mL.ConclusionThe combination of allicin and domiphen is an effective strategy for efficiently decreasing biofilms formation on various industrial materials surfaces.

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Section: Discussionmentioning

confidence: 99%

The combination of allicin with domiphen is effective against microbial biofilm formation

Li,

Wang,

et al. 2024

Front. Microbiol.

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“…For example, 65% of the causes affecting crop growth and yield are due to the development of drug-resistant pathogens. 3,4 Meanwhile, the presence of these chemicals such as antibacterial essential oil 5 and red copper oxide 6,7 ultimately leads to the contamination of agricultural soils, posing a serious threat to humans and the ecosystem, as both centralized and decentralized wastewater treatment systems do not target antimicrobial residues. 8 Fortunately, prevention of microbial infections through the development of novel, environment-friendly, low-toxic, or nontoxic antibacterial agents can solve the problem of ecological degradation in agricultural development.…”

Section: Introductionmentioning

confidence: 99%

“…However, there are some unanticipated problems, which affect the biological environment and constrain the development of agriculture. For example, 65% of the causes affecting crop growth and yield are due to the development of drug‐resistant pathogens 3,4 . Meanwhile, the presence of these chemicals such as antibacterial essential oil 5 and red copper oxide 6,7 ultimately leads to the contamination of agricultural soils, posing a serious threat to humans and the ecosystem, as both centralized and decentralized wastewater treatment systems do not target antimicrobial residues 8 .…”

Section: Introductionmentioning

confidence: 99%

Acrylic thiazole copolymer microspheres with “cluster effect” for long‐lasting antimicrobial activity and plant growth promotion

Zhang,

Zhu,

Geng

et al. 2023

J of Applied Polymer Sci

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The environmentally friendly, low toxic or nontoxic, and functional material to solve the needs of agricultural development are the key to current scientific research. Here, acrylic thiazole copolymer clusters (AcTPCs) were successfully synthesized by using common methacrylic acid as an induced source, combined with the antimicrobial monomers acrylic thiazole (AcT) and Zn2+, which are of great value for agricultural applications. Utilizing the “cluster effect,” under the synergistic effect of the fully exposed active ingredients, they not only have long‐lasting antimicrobial effects against bacteria and fungi, but also promote the growth of plant roots and stems and increase the chlorophyll content. Therefore, this study provides a novel, environmental‐friendly, and low‐toxic method to solve the microbe infection problem, which is expected to improve the agriculture.

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“…Polypropylene and polyvinyl chloride are difficult to degrade directly and pollute the environment. 7 In the recent 10 years, biodegradable materials as biopolymers instead of synthetic materials have attracted more and more attention all over the world. This urges the scientific and industrial circles to find a good and cost-effective method to replace traditional materials in some engineering applications.…”

Section: Introductionmentioning

confidence: 99%

Effect of different forms on geogrid tensile properties based on 3D printing technology

Gao

Yan

Zhang

et al. 2022

Journal of Thermoplastic Composite Materials

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Plastic materials are widely used as geosynthetics. The use of plastic products poses a serious environmental risk due to their degradation. Aiming at the environmental problems caused by the difficulty of direct degradation of traditional plastic geogrid and the effects of material filling ratios, material filling forms, mesh shapes and tensile rates on the mechanical properties of geogrids. Based on 3D printing technology, polylactic acid (PLA) geogrid was prepared, and indoor tensile tests of polylactic acid geogrid were carried out. The effects of material filling ratios, material filling forms, geogrid geometries and tensile rates on the mechanical properties of geogrid are analyzed. The test results showed that PLA can be used as an environmentally friendly material for making geogrids and can reflect the mechanical properties of different geogrids. The triaxial geogrid had the greatest tensile strength, while the uniaxial one had the least. The tensile strength of triaxial and biaxial geogrids increased with the increase of tensile rates, while uniaxial decreased and then increased. The elongation at break of uniaxial and triaxial geogrids increased with increasing tensile rates, while biaxial increased and then decreased. With the increase of filling ratios, the tensile strength of geogrid increased and then decreased. For the line 45 angle printed geogrid, the elongation at break increased first and then decreased and finally increased.

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New advances into antimicrobial research

Cited by 3 publications

References 11 publications

The combination of allicin with domiphen is effective against microbial biofilm formation

The combination of allicin with domiphen is effective against microbial biofilm formation

Acrylic thiazole copolymer microspheres with “cluster effect” for long‐lasting antimicrobial activity and plant growth promotion

Effect of different forms on geogrid tensile properties based on 3D printing technology

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