New approach for the assessment of cluster diets

Sy, Mouhamadou Moustapha; Feinberg, Max; Verger, P; Barré, Tangui; Clémençon, Stephan; Crépet, Amélie

doi:10.1016/j.fct.2012.11.005

Cited by 37 publications

(26 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This allowed us to estimate the expected predictive accuracy of imputation methods in practice. We classified countries according to 17 food consumption clusters, using the Global Environment Monitoring System’s Food contamination monitoring and assessment programme 14 . All except 19 countries had been assigned to a food cluster.…”

Section: Methodsmentioning

confidence: 99%

Data-driven methods for imputing national-level incidence in global burden of disease studies

McDonald

Devleesschauwer

Speybroeck

et al. 2015

Bull. World Health Organ.

View full text Add to dashboard Cite

ObjectiveTo develop transparent and reproducible methods for imputing missing data on disease incidence at national-level for the year 2005.MethodsWe compared several models for imputing missing country-level incidence rates for two foodborne diseases – congenital toxoplasmosis and aflatoxin-related hepatocellular carcinoma. Missing values were assumed to be missing at random. Predictor variables were selected using least absolute shrinkage and selection operator regression. We compared the predictive performance of naive extrapolation approaches and Bayesian random and mixed-effects regression models. Leave-one-out cross-validation was used to evaluate model accuracy.FindingsThe predictive accuracy of the Bayesian mixed-effects models was significantly better than that of the naive extrapolation method for one of the two disease models. However, Bayesian mixed-effects models produced wider prediction intervals for both data sets.ConclusionSeveral approaches are available for imputing missing data at national level. Strengths of a hierarchical regression approach for this type of task are the ability to derive estimates from other similar countries, transparency, computational efficiency and ease of interpretation. The inclusion of informative covariates may improve model performance, but results should be appraised carefully.

show abstract

Section: Methodsmentioning

confidence: 99%

Data-driven methods for imputing national-level incidence in global burden of disease studies

McDonald

Devleesschauwer

Speybroeck

et al. 2015

Bull. World Health Organ.

View full text Add to dashboard Cite

show abstract

“…1, Table Supplemental material). Whether these differences are related to differences in national contamination level of the environment or foods available on the market, or to differences in lifestyle or dietary patterns is not clear Sy et al, 2013).…”

Section: P-valuementioning

confidence: 99%

Exposure determinants of cadmium in European mothers and their children

Berglund

Larsson

Grandér

et al. 2015

Environmental Research

View full text Add to dashboard Cite

The metal cadmium (Cd) is a widespread environmental pollutant with documented adverse effects on the kidneys and bones from long-term environmental exposure, but with insufficiently elucidated public health consequences such as risk of cardiovascular disease, hormone-related cancer in adults and developmental effects in children. This study is the first pan-European human biomonitoring project that succeeded in performing harmonized measurements of Cd in urine in a comparable way in mother-child couples from 16 European countries. The aim of the study was to evaluate the overall Cd exposure and significant determinants of Cd exposure. A study population of 1632 women (24-52 years of age), and 1689 children (5-12 years of age), from 32 rural and urban areas, was examined within a core period of 6 months in 2011-2012. Women were stratified as smokers and non-smokers. As expected, smoking mothers had higher geometric mean (gm) urinary cadmium (UCd; 0.24 µg/g crea; n=360) than non-smoking mothers (gm 0.18 µg/g crea; n=1272; p<0.0001), and children had lower UCd (gm 0.065 µg/g crea; n=1689) than their mothers at the country level. Non-smoking women exposed to environmental tobacco smoke (ETS) at home had 14% (95% CI 1-28%) higher UCd than those who were not exposed to ETS at home (p=0.04). No influence of ETS at home or other places on UCd levels was detected in children. Smoking women with primary education as the highest educational level of the household had 48% (95% CI 18-86%) higher UCd than those with tertiary education (p=0.0008). The same observation was seen in non-smoking women and in children; however they were not statistically significant. In children, living in a rural area was associated with 7% (95% CI 1-13%) higher UCd (p=0.03) compared to living in an urban area. Children, 9-12 years had 7% (95% CI 1-13%) higher UCd (p=0.04) than children 5-8 years. About 1% of the mothers, and 0.06% of the children, exceeded the tolerable weekly intake (TWI) appointed by EFSA, corresponding to 1.0 µg Cd/g crea in urine. Poland had the highest UCd in comparison between the 16 countries, while Denmark had the lowest. Whether the differences between countries are related to differences in the degree of environmental Cd contamination or to differences in lifestyle, socioeconomic status or dietary patterns is not clear.

show abstract

“…For the mean consumption, a database on per capita data (FAO 2013) and grouped in 17 cluster diets (Sy et al 2013) can also be used. For a given food category, the highest value extracted from the cluster diets or reported from an individual food consumption survey is used.…”

Section: Gecde: Estimating Chronic Exposurementioning

confidence: 99%

Characterizing chronic and acute health risks of residues of veterinary drugs in food: latest methodological developments by the joint FAO/WHO expert committee on food additives

Boobis

Cerniglia

Chicoine

et al. 2017

Critical Reviews in Toxicology

Self Cite

View full text Add to dashboard Cite

The risk assessment of residues of veterinary drugs in food is a field that continues to evolve. The toxicological end-points to be considered are becoming more nuanced and in light of growing concern about the development of antimicrobial resistance, detailed analysis of the antimicrobial activity of the residues of veterinary drugs in food is increasingly incorporated in the assessment. In recent years, the Joint FAO/WHO Expert Committee on Food Additives (JECFA) has refined its approaches to provide a more comprehensive and fit-for-purpose risk assessment. This publication describes in detail the consideration of acute and chronic effects, the estimation of acute and chronic dietary exposure, current approaches for including microbiological endpoints in the risk assessment, and JECFA's considerations for the potential effects of food processing on residues from veterinary drugs. JECFA now applies these approaches in the development of health-based guidance values (i.e. safe exposure levels) for residues of veterinary drugs. JECFA, thus, comprehensively addresses acute and chronic risks by using corresponding estimates for acute and chronic exposure and suitable correction for the limited bioavailability of bound residues by the Gallo-Torres model. On a case-by-case basis, JECFA also considers degradation products that occur from normal food processing of food containing veterinary drug residues. These approaches will continue to be refined to ensure the most scientifically sound basis for the establishment of health-based guidance values for veterinary drug residues.ARTICLE HISTORY

show abstract

New approach for the assessment of cluster diets

Cited by 37 publications

References 14 publications

Data-driven methods for imputing national-level incidence in global burden of disease studies

Data-driven methods for imputing national-level incidence in global burden of disease studies

Exposure determinants of cadmium in European mothers and their children

Characterizing chronic and acute health risks of residues of veterinary drugs in food: latest methodological developments by the joint FAO/WHO expert committee on food additives

Contact Info

Product

Resources

About