New Approaches to the Application of DART Mass Spectrometry Coupled with Planar Chromatography for the Analysis of Mixtures of Organic Compounds

Recent Advances in Combinations of TLC With MALDI and Other Desorption/Ionization Mass-Spectrometry Techniques

“…The first version of the commercial DART ion source was inconvenient for TLC analysis because the gas stream was directed to the orifice of the MS interface and the analysis required cutting of the plates. Though a special adapter increases the efficiency of desorption/ionization and reproducibility of the results was proposed by Ovcharov et al (2017), the problem was completely overcome with the release of new generation of DART ion sources, allowing to change the gas flow angle (so-called reflection scanning) and having TLC holders (Figure 6). The sensitivity of TLC/DART can also be increased using shortened source caps .…”