New Aspects of DNA-based Authentication of Chinese Medicinal Plants by Molecular Biological Techniques

Heubl, Günther

doi:10.1055/s-0030-1250519

Cited by 136 publications

(111 citation statements)

References 178 publications

(184 reference statements)

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“…The methods of classical botany for plant identification are recently supplemented by various DNA-based technologies, including RAPD, RFLP, ARMS, CAPS, AFLP, DAF, ISSR, SSR, hybridization and microarrays [6]. A recent technological development is the authentication of medicinal plants by barcode DNA.…”

Section: Dna-based Technologiesmentioning

confidence: 99%

Quality Control for Medicinal Plants

Efferth

Greten²

2012

Med Aromat Plants

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Section: Dna-based Technologiesmentioning

confidence: 99%

Quality Control for Medicinal Plants

Efferth

Greten²

2012

Med Aromat Plants

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“…Subsequent years (2004-2007) sought, moreover, authentication, fingerprinting, and quality control of herbs. Likewise, metabolomic profiling was also concurrently employed to substantiate data on identification and fingerprinting [7][8][9][10][11][12]. It was not, however, before 2008 when omics were introduced to boost the yet traditional herbal activity studies.…”

Section: Page 2 Ofmentioning

confidence: 99%

Herbal Therapy: Can Omics Technology Create Order from Chaos?

El‐Mowafy¹

2012

Biochem Anal Biochem

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“…Advance practice of genomic authentication has extended the scope of pharmacognostical science (Heubl, 2010) to molecular level, so it should be added as a parameter to control quality of drugs of natural origin (Huang, 2012).…”

Section: Introductionmentioning

confidence: 99%

Authentication of polyherbal formulations using PCR technique

Butt¹,

Ishtiaq²,

Ijaz³

et al. 2018

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Unprecedented growth in popularity of complementary medicines raised concerns about their quality and safety. So, there is need to develop methods for their sensitive, specific and accurate analysis. Authenticity and similarity of medicinal nutrients and strict procedures of material handling are significant features to maintain the quality of herbal preparations. Genome based methods to authenticate these plants revolutionized the authentication process. Developing DNA molecular markers by sequencing a standard zone of the DNA is the best technique to identify the adulterants as well as to authenticate the required species of medicinal plants. Application of molecular biological technique serves as one of the very consistent system for authentication of natural herbal materials. The progress of authentic analytical methods is a major challenge to scientists as natural products are optimized as drug like molecules. This research work is based on the application of PCR technique for authentication of Glycyrrhiza glabra L. in its crude form as well as in final dosage form, i.e., Hamdard's Joshanda, Marhaba's Joshanda, GNC herbal supplement and Joshaba Sadar (Chest tea) available in market, provided isolated DNA from dried roots of the sample was used as templates in PCR. All the products gave the desired results except one. It proved to be a complementary tool to control quality of herbal materials alone and in different marketable herbal product having Glycyrrhiza spp. as their active ingredient.

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New Aspects of DNA-based Authentication of Chinese Medicinal Plants by Molecular Biological Techniques

Cited by 136 publications

References 178 publications

Quality Control for Medicinal Plants

Quality Control for Medicinal Plants

Herbal Therapy: Can Omics Technology Create Order from Chaos?

Authentication of polyherbal formulations using PCR technique

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