New Avian Paramyxoviruses Type I Strains Identified in Africa Provide New Outcomes for Phylogeny Reconstruction and Genotype Classification

Almeida, Renata Servan de; Hammoumi, Saliha; Gil, Patricia; Briand, François-Xavier; Molia, Sophie; Gaidet, Nicolas; Cappelle, Julien; Chevalier, Véronique; Balança, Gilles; Traoré, Abdallah; Grillet, Colette; Maminiaina, Olivier Fridolin; Guendouz, Samia; Dakouo, Marthin; Samaké, K.; Bezeid, Ould El Mamy; Diarra, Abbas; Chaka, Hassen; Goutard, Flavie; Thompson, Peter N.; Martinez, Dominique; Jestin, Véronique; Albina, Emmanuel

doi:10.1371/journal.pone.0076413

Cited by 52 publications

(52 citation statements)

References 49 publications

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“…The introduction of seemingly healthy, but inadvertently infected new bird to an existing flock has been reported to result in an outbreak of ND and highly pathogenic avian influenza (NVRI unpublished data, 2006). Also, reports of isolation of virulent NDV from apparently healthy birds have been documented [18,22,28,62,99]. In all of these reports, free-range local chickens and ducks were involved.…”

Section: Epizootiology Of Nd In Nigeriamentioning

confidence: 99%

Newcastle disease in Nigeria: epizootiology and current knowledge of circulating genotypes

2016

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Over the years, Newcastle disease (ND) has defied all available control measures. The disease has remained at the forefront of infectious diseases afflicting poultry production after avian influenza. Despite the continuous global use of million doses of ND vaccine annually, the causative pathogen, avian paramyxovirus type 1 also known as Newcastle disease virus (NDV) has continued to evolve causing, even more, a threat not only to the unvaccinated but the vaccinated flocks inclusive. The disease has been well studied in the developed countries where the virus is found in circulation. However, limited information exists on the epizootiology and circulating genotypes of the virus in developing countries where the majority of the flocks are raised on the extensive management system. Identification of virulent NDV in apparently healthy free-range ducks in this system calls for concern and pragmatic approach to investigate factor(s) that favour the virus inhabiting the ducks without clinical manifestation of the disease. Recently, novel genotypes (XIV, XVII, and XVIII) with peculiarity to West and Central African countries have been discovered and due to lack or poor surveillance system possibility of hitherto unreported genotypes are likely. This review elucidates and discusses available literature on the diversity of the circulating NDV genotypes across the West Africa countries and the epizootiology (molecular) of the disease in Nigeria with the view of identifying gaps in knowledge that can assist in the development of effective vaccines and control strategies to combat the peril of the disease.

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Section: Epizootiology Of Nd In Nigeriamentioning

confidence: 99%

Newcastle disease in Nigeria: epizootiology and current knowledge of circulating genotypes

2016

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“…After 1-3 passages, allantoic liquid from dead eggs was tested by NDV RT-qPCR, and NDV-positive samples were then stored at −80 °C and used as working stock for sequence analysis. More details on the methods are published in de Almeida et al [4]. All samples collected in Zimbabwe were analysed at Onderstepoort Veterinary Institute (OVI) Laboratory, Onderstepoort, South Africa following a common procedure for collection, storage and shipment.…”

Section: Sampling and Diagnostic Proceduresmentioning

confidence: 99%

Empirical analysis suggests continuous and homogeneous circulation of Newcastle disease virus in a wide range of wild bird species in Africa

et al. 2014

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SUMMARYNewcastle disease (ND) is one of the most important poultry diseases worldwide and can lead to annual losses of up to 80% of backyard chickens in Africa. All bird species are considered susceptible to ND virus (NDV) infection but little is known about the role that wild birds play in the epidemiology of the virus. We present a long-term monitoring of 9000 wild birds in four African countries. Overall, 3·06% of the birds were PCR-positive for NDV infection, with prevalence ranging from 0% to 10% depending on the season, the site and the species considered. Our study shows that ND is circulating continuously and homogeneously in a large range of wild bird species. Several genotypes of NDV circulate concurrently in different species and are phylogenetically closely related to strains circulating in local domestic poultry, suggesting that wild birds may play several roles in the epidemiology of different NDV strains in Africa. We recommend that any strategic plan aiming at controlling ND in Africa should take into account the potential role of the local wild bird community in the transmission of the disease.

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“…O genotipo XI é proveniente de estirpes isoladas de Madagascar (MAMINIAINA et al, 2010;DE ALMEIDA et al, 2013). Estes vírus são classificados como velogênicos pelo sequenciamento gênico, embora tenham sido detectados de aves domésticas (frangos) sadias não vacinadas e de aves doentes (MAMINIAINA et al, 2010;DE ALMEIDA et al, 2013).…”

Section: Doença De Newcastleunclassified

“…Estes vírus são classificados como velogênicos pelo sequenciamento gênico, embora tenham sido detectados de aves domésticas (frangos) sadias não vacinadas e de aves doentes (MAMINIAINA et al, 2010;DE ALMEIDA et al, 2013).…”

Section: Doença De Newcastleunclassified

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<b>Detecção e caracterização moleculares dos paramixovírus aviários tipo 1 em materiais provenientes de aves silvestres utilizando testes para a detecção dos vírus da família viral Paramyxoviridae</b>

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AGRADECIMENTOSAgradeço primeiramente aos meus pais e irmãos pelo apoio recebido durante esta fase tão importante na minha vida.À minha orientadora Profa Dra. Helena Lage Ferreira, pela confiança, pela atenção e dedicação a mim em todos os momentos que precisei e principalmente a paciência para me orientar e me passar todos os conhecimentos que tenho hoje. Muito, muito, muito obrigada! Agradeço a todos do Laboratório Multiusuário de Saúde Animal e Segurança Alimentar pelos nossos momentos juntos. Em especial a Vanessa maravilhosa, sempre alegrando o laboratório e dando dicas valiosas. À Julia, a melhor técnica do mundo e a mais forte, que sempre disposta a nos ajudar dentro e fora do laboratório e pela sua amizade. Ao Guilherme, sempre me ajudando, tirando minhas dúvidas e curiosidades. Ao Raphael e a Laís, nós formamos o trio parada dura. Nossas rodas de discussão, apoios dentro e fora do laboratório, nossas tardes de trabalho e nossa amizade.Aos que fizeram meus dias em Pirassununga especiais, divertidos e menos solitários: Erika, Eduardo, Emily, Matar, Cury, Bruna, Atanásio, entre outros.A todos os professores que fizeram parte da minha formação cientifica e principalmente ao Prof Dr. Ricardo Albuquerque, por ter apresentado a orientadora maravilhosa que tenho hoje e por me incentivar sempre. PCR were successfully validated, however they had differences in the limit of detection when compared to specific RRT-PCR assays using different viruses. In total, 100 wild bird samples (swabs) were tested by the selected RT-PCR with similar limit of detection between tested viruses. Two samples were positive by this test and they were also detected by the specific RRT-PCR for NDV. These samples were closed related to vaccinal NDV strains belonging to genotype II class II. Deduced amino acid sequences of cleavage site region from detected samples were characterized as lentogenic NDV strains ( 113 RQGR ↓ L 117 ). Our study demonstrates the poor biosafety used by poultry industry allowing the vaccinal escape to wild bird species.

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New Avian Paramyxoviruses Type I Strains Identified in Africa Provide New Outcomes for Phylogeny Reconstruction and Genotype Classification

Cited by 52 publications

References 49 publications

Newcastle disease in Nigeria: epizootiology and current knowledge of circulating genotypes

Newcastle disease in Nigeria: epizootiology and current knowledge of circulating genotypes

Empirical analysis suggests continuous and homogeneous circulation of Newcastle disease virus in a wide range of wild bird species in Africa

<b>Detecção e caracterização moleculares dos paramixovírus aviários tipo 1 em materiais provenientes de aves silvestres utilizando testes para a detecção dos vírus da família viral Paramyxoviridae</b>

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