New Bioabsorbable Polylactide Ureteral Stent in the Treatment of Ureteral Lesions: An Experimental Study

Lumiaho, Juha; Heino, Antero; Tunninen, Virpi; Ala‐Opas, Martti; Talja, Martti; Välimaa, Tero; Tormala, P.

doi:10.1089/end.1999.13.107

Cited by 51 publications

(22 citation statements)

References 23 publications

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“…Poly-L, D-lactide ureteral stents used in animal studies dissolved in 6±12 weeks without signi®cant obstruction during the biodegradation process [31]. Another polylactide material tested in vitro was designed for biodegradation in alkaline environment.…”

Section: Urological Biomaterials and Biocompatibilitymentioning

confidence: 99%

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Advances in ureteral stent technology

Denstedt¹,

Reid

Sofer³

2000

World J Urol

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This review focuses on technological advances and relevant research related to ureteral stents. The importance of physical and chemical biomaterial type, biocompatibility, material coatings such as hydrogels, and infection related to indwelling ureteral stents are discussed. Recent in vitro and in vivo research has focused on materials that will reduce encrustation and bacterial biofilm formation. The adsorption of antimicrobials onto devices holds promise of reducing infection rates, but multidrug resistant bacteria, short leaching times and adverse side effects make it essential that alternative strategies be investigated. Just so, encrustation limits the long-term use of urinary materials, and a better understanding of factors involved in encrustation are needed to reduce the problem.

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Section: Urological Biomaterials and Biocompatibilitymentioning

confidence: 99%

“…Another stent incorporating a distal magnetic tip can be retrieved, using a magnet [32]. The development of biodegradable stents will eliminate the need for invasive removal procedures [31,59].…”

Section: Design Shape And¯ow Studiesmentioning

confidence: 99%

Advances in ureteral stent technology

Denstedt¹,

Reid

Sofer³

2000

World J Urol

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“…This is true for bioabsorbable stent material (PLA 96) which has been used in association with polyglycolide for years in absorbable sutures. Polylactide stents have been reported to reduce infections as compared with traditional stents [7,8] .…”

Section: Introductionmentioning

confidence: 99%

Biocompatibility of a New Bioabsorbable Radiopaque Stent Material (Ba SO4 Containing Poly-L,D-Lactide) in the Rat Pancreas

et al. 2006

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“…Healing the transverse cut on beagles by applying a self-expandable, self-reinforced poly-L , D -lactide partial ureteral stent (SR-PLA 96) reveals that stent tube does not affect urinary tract dynamics; and the stent's tissue compatibility is almost equal to that for double-J stent, preventing the reflux where ureters meet bladders [20][21][22]. In one study, a temporary ureteral drainage stent was applied to percutaneous nephrolithotripsy.…”

Section: Discussionmentioning

confidence: 99%

“…With the development of biodegradable polymers and their use for urinary stents [9][10][11][12][13][14][15][16], there has been progress in research on application of polylactic acid for ureteral stents [17][18][19][20][21][22][23][24][25]. Biodegradable polymers, with greater biocompatibility, can degrade in vivo , which obviates the need for a second procedure for stent removal and has good safety.…”

Section: Introductionmentioning

confidence: 99%

Introduction to biodegradable polylactic acid ureteral stent application for treatment of ureteral war injury

Li¹,

Wang²,

Fu³

et al. 2011

BJU International

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These authors contributed equally to the study the other side was debrided and sutured without stenting.• Both IVP and radioactive renography were performed 40, 80 and 120 days postoperatively. The operability and effectiveness of the biodegradable ureteral stent were studied thereafter. RESULTS• In Group A, hydronephrosis and hydroureter occurred and worsened postoperatively on the wounded sides in all nine beagles. The ratio of the renal partial concentration indices (RPCI) between the kidneys (unwounded side : wounded side) increased.• The ratio of the kidney washout half-time between the kidneys (unwounded side : wounded side) decreased. In Group B, neither hydronephrosis nor hydroureter was found postoperatively in the stented ureters but both occurred in the unstented ureters in all nine beagles.• The ratio of RPCI between kidneys (stented side : unstented side) increased whereas the kidney washout half-time ratio between the stented and unstented sides decreased. Differences were significant. CONCLUSION• In Group A, the new canine model for firearm fragment wounds was tested and proved to be operable and effective. In Group B, hydronephrosis and hydroureter were effectively prevented in ureters by biodegradable stent placement compared with the non-stented ureters where hydronephrosis and hydroureter occurred. The renal concentration capacity was effectively protected and the half-time of kidney washout was shortened.

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New Bioabsorbable Polylactide Ureteral Stent in the Treatment of Ureteral Lesions: An Experimental Study

Cited by 51 publications

References 23 publications

Advances in ureteral stent technology

Advances in ureteral stent technology

Biocompatibility of a New Bioabsorbable Radiopaque Stent Material (Ba SO4 Containing Poly-L,D-Lactide) in the Rat Pancreas

Introduction to biodegradable polylactic acid ureteral stent application for treatment of ureteral war injury

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